Application of vascularized perforant flaps in the hand restoration in electro-thermic affections

Kovalenko, O.M.; Zhernov, О. А.

doi:10.26779/2522-1396.2020.11-12.71

Cited by 3 publications

(1 citation statement)

References 4 publications

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“…Порушення складних фізіологічних механізмів кисті, які забезпечують її багатосторонню діяльність, призводять до втрати працездатності, тяжких психічних розладів, глибокої інвалідності у 19-22,5% постраждалих [186,187]. Сучасні технології лікування опіків в гострому періоді дозволили значно знизити частоту опікових деформацій з 40-43% до 18-20% [188]. Однак, найбільш часто хірургічна реабілітація здійснюється з приводу післяопікових згинальних контрактур кистей (40%) [189,190].…”

Section: патогенетичне обгрунтування хірургічного лікування післяопік...unclassified

Scientific Foundations in medicine and Pharmacy

Vladlenov¹

2022

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All rights reserved. Printed in the United States of America. No part of this publication may be reproduced, distributed, or transmitted, in any form or by any means, or stored in a data base or retrieval system, without the prior written permission of the publisher. The content and reliability of the articles are the responsibility of the authors. When using and borrowing materials reference to the publication is required. Collection of scientific articles published is the scientific and practical publication, which contains scientific articles of students, graduate students, Candidates and Doctors of Sciences, research workers and practitioners from Europe and Ukraine. The articles contain the study, reflecting the processes and changes in the structure of modern science.

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Section: патогенетичне обгрунтування хірургічного лікування післяопік...unclassified

Scientific Foundations in medicine and Pharmacy

Vladlenov¹

2022

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Design and testing of an optical instrument for skin flap monitoring

Moreno-Oyervides,

Díaz-Ojeda,

Bonilla-Manrique

et al. 2023

Sci Rep

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Flap procedures are complex surgical tools widely used in reconstructive surgery. Flap ischemia is one of the most dangerous complications, both during the surgical procedure and during the patient's recovery, which can quickly lead to tissue necrosis (flap loss) with serious medical and psychological consequences. Today, bedside clinical assessment remains the gold standard for flap monitoring, but timely detection of flap ischemia is a difficult and challenging task, so auxiliary techniques are needed to support flap monitoring. Here we present a prototype of a new optical diagnostic tool, based on visible light absorption in diffuse reflectance spectroscopy, for non-invasive, continuous, real-time monitoring of flaps. The proposed approach is assessed by monitoring flap ischemic scenarios induced on pig animal models. The results obtained support that the proposed approach has great potential, not only for prompt detection of ischemia (in seconds), but also for clear differentiation between an arterial occlusion and venous occlusion.

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Anatomical and Functional Characteristics of Complex Flaps of the Subclavian Artery Basin in Reconstructive Surgery of the Head and Neck

Fedzhaga,

Kravets,

Pivtorak

et al. 2024

VPBM

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Introduction. Despite the number of conducted studies, the study of intrauterine development of the spinal cord does not lose its relevance. It is one of the structures of the central nervous system, which ensures the interconnection of the structures of the human body with the brain. Also, it provides the transmission of all types of sensitivity and motor impulses. In addition, there was an opportunity to compare recently obtained data with data from ten years ago and perform further in-depth analysis. The study of embryogenesis makes it possible to identify the causes and mechanisms of birth defects of the spinal cord, which is important for the development of their diagnosis, treatment and preventive measures methods. Immunohistochemical methods play the main role, and are important for progress in medicine and biology, as they allow researchers to accurately and specifically study changes in tissues.Object and research methods. 134 preparations of human embryos and fetuses aged from 6-7 to 39-40 weeks of intrauterine development were studied using the immunohistochemical method. Monoclonal antibodies from the company "DacoCytomation" (Denmark) were chosen for the study: vimentin, synaptophysin, Ki-67, CDX2, S-100.The results. The 5-6th week of gestation is characterized by active proliferation processes, which is why a strong expression of Ki-67 was observed. In the future, the proliferation processes gradually fade away, which is directly proportional to the expression of Ki-67. As for S-100, in the embryonic period the expression is weakly expressed and begins to increase and is noted as strong from the 14-15th week of gestation. As for vimentin and CDX-2, they are characterized by strong expression at the end of the embryonic period.Conclusions. Based on the results of immunohistochemical methods, it was found that before the end of the period of intrauterine development, the expression of Ki-67 is weak, and vimentin and CDX-2 are completely absent. Instead, the expression of S-100 and synaptophysin in the studied nuclei is alternately relatively strong.

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Application of vascularized perforant flaps in the hand restoration in electro-thermic affections

Cited by 3 publications

References 4 publications

Scientific Foundations in medicine and Pharmacy

Scientific Foundations in medicine and Pharmacy

Design and testing of an optical instrument for skin flap monitoring

Anatomical and Functional Characteristics of Complex Flaps of the Subclavian Artery Basin in Reconstructive Surgery of the Head and Neck

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