Application of wild Saudi plant extracts to control antibiotic resistant Staphylococcus aureus

Al-Saggaf, Mohammed S.

doi:10.5455/egyjebb.20180102120515

Cited by 2 publications

(2 citation statements)

References 19 publications

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“…Interestingly, the authors also performed analyzes that evaluated the possibility of using B. eriophora extract to create an antibacterial layer on textiles against S. aureus. Furthermore, they indicate that anti-S. aureus fabrics do not lose their antibacterial properties, even after two washing cycles (prepared according to the test method 61(2A)-1996, the American Association of Textile Chemists and Colorists) (Alsaggaf et al 2018). The potential of B. scoparia for MRSA was also investigated.…”

Section: Antibacterial Antifungal and Antiparasitic Activitymentioning

confidence: 99%

Current knowledge on genus Bassia All.: a comprehensive review on traditional use, phytochemistry, pharmacological activity, and nonmedical applications

et al. 2023

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Bassia All. is a genus from the Amaranthaceae family, which was created by merging selected species belonging to the former Bassia and Kochia genera with those classified to Chenolea, Londesia, Kirilowia and Panderia. The reorganised Bassia genus currently comprises around 20 species, which are annual herbs or perennial subshrubs native to Eurasia and Africa. Bassia plants are well known for their therapeutic applications in folk medicine and traditional medical systems, and they are also used for nonmedical purposes. Some members of this genus, such as Bassia scoparia (syn. Kochia scoparia) is of great medical importance and economic value. The plant is cultivated in some regions of Asia as a crop to collect Kochiae fructus, which is used for both curative and food purposes. Phytochemical studies carried out on Bassia species indicate that these plants synthesize metabolites belonging to different groups of compounds (e.g., triterpene saponins, sterols, flavonoids, fatty acids, lignanamides, alkaloids, organic acids). Some of the structures are rarely found in the plant kingdom. Biological activity studies carried out on Bassia plants revealed various effects exerted by extracts and isolated compounds, including anti-inflammatory, cytotoxic, antioxidant, antimicrobial, hypoglycemic, anti-obesity, etc. Modern research explained some of the mechanisms of action. This review covers literature from 1935 to 2022, and assembles and discusses data on phytochemistry, biological activity, as well as medical and nonmedical use of the representatives of the genus Bassia. In this review we present the current state of knowledge about the plants of the genus.

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Section: Antibacterial Antifungal and Antiparasitic Activitymentioning

confidence: 99%

Current knowledge on genus Bassia All.: a comprehensive review on traditional use, phytochemistry, pharmacological activity, and nonmedical applications

et al. 2023

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“…Previous reports have demonstrated that extracts from Ducrosia plant species possessed good-to-moderate susceptibility against S. epidermidis ATCC 49461, B. cereus ATCC 10876, S. aureus clinical isolate and S. aureus ATCC 25923 [ 26 ]. Similarly, Alsaggaf [ 27 ] reported that D. anethifolia extract was able to inhibit the growth of both methicillin sensitive and methicillin resistant S. aureus strains with a diameter of growth inhibition zone ranging from (7.8 ± 0.4) mm for MRSA2 strain to (9.6 ± 0.6) mm, as compared to S. aureus ATCC 25923 (10.2 ± 0.5 mm). Al-Whibi and colleagues [ 22 ] studied the antimicrobial activities of D. anethifolia (leaves and fruit methanolic and acetone extracts) against S. aureus ATCC 25923, methicillin resistant S. aureus MRSA ATCC 12498, B. subtilis (ATCC 6633), E. feacalis ATCC 29122, E. coli ATCC 25966, P. aeruginosa ATCC 27853, K. pneumoniae ATCC 700603, Salmonella sp.…”

Section: Discussionmentioning

confidence: 99%

Chemical Composition of Ducrosia flabellifolia L. Methanolic Extract and Volatile Oil: ADME Properties, In Vitro and In Silico Screening of Antimicrobial, Antioxidant and Anticancer Activities

et al. 2022

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In the present study, the chemical composition of the volatile oil and methanolic extract from Ducrosia flabellifolia Boiss. was investigated. The antimicrobial, antioxidant, and anticancer activities of the methanolic extract from D. flabellifolia aerial parts were screened using experimental and computational approaches. Results have reported the identification of decanal (28.31%) and dodecanal (16.93%) as major compounds in the essential oil obtained through hydrodistillation. Farnesyl pyrophosphate, Methyl 7-desoxypurpurogallin-7-carboxylate trimethyl ether, Dihydro-Obliquin, Gummiferol, 2-Phenylaminoadenosine, and 2,4,6,8,10-dodecapentaenal, on the other hand, were the dominant compounds in the methanolic extract. Moreover, the tested extract was active against a large collection of bacteria and yeast strains with diameter of growth inhibition ranging from 6.67 ± 0.57 mm to 17.00 ± 1.73 mm, with bacteriostatic and fungicidal activities against almost all tested microorganisms. In addition, D. flabellifolia methanolic extract was dominated by phenolic compounds (33.85 ± 1.63 mg of gallic acid equivalent per gram of extract) and was able to trap DPPH• and ABTS•+ radicals with IC50 about 0.05 ± 0 mg/mL and 0.105 ± 0 mg/mL, respectively. The highest percentages of anticancer activity were recorded at 500 µg/mL for all cancer cell lines with IC50 about 240. 56 µg/mL (A-549), 202.94 µg/mL (HCT-116), and 154.44 µg/mL (MCF-7). The in-silico approach showed that D. flabellifolia identified compounds bound 1HD2, 2XCT, 2QZW, and 3LN1 with high affinities, which together with molecular interactions and the bond network satisfactorily explain the experimental results using antimicrobial, antioxidant, and anticancer assays. The obtained results highlighted the ethnopharmacological properties of the rare desertic D. flabellifolia plant species growing wild in Hail region (Saudi Arabia).

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Application of wild Saudi plant extracts to control antibiotic resistant Staphylococcus aureus

Cited by 2 publications

References 19 publications

Current knowledge on genus Bassia All.: a comprehensive review on traditional use, phytochemistry, pharmacological activity, and nonmedical applications

Current knowledge on genus Bassia All.: a comprehensive review on traditional use, phytochemistry, pharmacological activity, and nonmedical applications

Chemical Composition of Ducrosia flabellifolia L. Methanolic Extract and Volatile Oil: ADME Properties, In Vitro and In Silico Screening of Antimicrobial, Antioxidant and Anticancer Activities

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