Application of zeolites and zeolitic imidazolate frameworks in the biosensor development

Кучеренко, І. С.; Солдаткін, О. О.; Dzyadevych, S. V.; Солдаткин, А. П.

doi:10.1016/j.bioadv.2022.213180

Cited by 14 publications

(3 citation statements)

References 50 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Due to its rapid electron transfer kinetics and large surface area, the Pec@ZIF-12/GCE has a higher peak current than other electrodes, which supports good redox behavior. Also, owing to the encapsulation of Pec inside the ZIF-12, it greatly enhanced the composite’s stability leading for increased redox behavior . The Pec exhibits low conductivity as a result of its amorphous nature, while ZIF also shows a better current value due to the presence of cobalt ion.…”

Section: Electrochemical Characterizationsmentioning

confidence: 99%

Natural Polymer Encapsulated Zeolitic Imidazolate Framework-12 Composite toward Electrochemical Sensing of Antitumor Agent

Thenrajan,

Madhu Malar,

Wilson

2024

ACS Appl. Bio Mater.

View full text Add to dashboard Cite

Encapsulation of natural polymer pectin (Pec) into a zeolitic imidazolate framework-12 (ZIF-12) matrix via a simple chemical method toward anticancer agent gallic acid (GA) detection is reported in this work. GA, a natural phenol found in many food sources, has gained attention by its biological effects on the human body, such as an antioxidant and anti-inflammatory. Therefore, it is crucial to accurately and rapidly determine the GA level in humans. The encapsulation of Pec inside the ZIF-12 has been successfully confirmed from the physiochemical studies such as XRD, Raman, FTIR, and XPS spectroscopy along with morphological FESEM, BET, and HRTEM characterization. Under optimized conditions, the Pec@ZIF-12 composite exhibits wide linear range of 20 nM−250 μM with a detection limit of 2.2 nM; also, it showed excellent selectivity, stability, and reproducibility. Furthermore, the real sample analysis of food samples including tea, coffee, grape, and pomegranate samples shows exceptional recovery percentage in an unspiked manner. So far, there is little literature for encapsulating proteins, enzymes, metals, etc., that have been reported; here, we successfully encapsulated a natural polymer Pec inside the ZIF-12 cage. This encapsulation significantly enhanced the composite electrochemical performance, which could be seen from the overall results. All of these strongly suggest that the proposed Pec@ZIF-12 composite could be used for miniaturized device fabrication for the evaluation of GA in both home and industrial applications.

show abstract

Section: Electrochemical Characterizationsmentioning

confidence: 99%

Natural Polymer Encapsulated Zeolitic Imidazolate Framework-12 Composite toward Electrochemical Sensing of Antitumor Agent

Thenrajan,

Madhu Malar,

Wilson

2024

ACS Appl. Bio Mater.

View full text Add to dashboard Cite

show abstract

“…When hydrogels are combined with zeolites, they can provide a stable and biocompatible platform for the immobilization of enzymes and other biomolecules [ 89 ]. The high-water content of hydrogels ensures that the biomolecules remain hydrated and active, while the zeolites provide porous support for the immobilization of enzymes and other biomolecules [ 90 ]. This combination of hydrogels and zeolites has led to the development of highly sensitive and selective electrochemical biosensors for a wide range of analytes.…”

Section: Materials For Electrochemical Wearable Biosensorsmentioning

confidence: 99%

Electrochemical Wearable Biosensors and Bioelectronic Devices Based on Hydrogels: Mechanical Properties and Electrochemical Behavior

Saeidi,

Chenani,

Orouji

et al. 2023

Biosensors

View full text Add to dashboard Cite

Hydrogel-based wearable electrochemical biosensors (HWEBs) are emerging biomedical devices that have recently received immense interest. The exceptional properties of HWEBs include excellent biocompatibility with hydrophilic nature, high porosity, tailorable permeability, the capability of reliable and accurate detection of disease biomarkers, suitable device–human interface, facile adjustability, and stimuli responsive to the nanofiller materials. Although the biomimetic three-dimensional hydrogels can immobilize bioreceptors, such as enzymes and aptamers, without any loss in their activities. However, most HWEBs suffer from low mechanical strength and electrical conductivity. Many studies have been performed on emerging electroactive nanofillers, including biomacromolecules, carbon-based materials, and inorganic and organic nanomaterials, to tackle these issues. Non-conductive hydrogels and even conductive hydrogels may be modified by nanofillers, as well as redox species. All these modifications have led to the design and development of efficient nanocomposites as electrochemical biosensors. In this review, both conductive-based and non-conductive-based hydrogels derived from natural and synthetic polymers are systematically reviewed. The main synthesis methods and characterization techniques are addressed. The mechanical properties and electrochemical behavior of HWEBs are discussed in detail. Finally, the prospects and potential applications of HWEBs in biosensing, healthcare monitoring, and clinical diagnostics are highlighted.

show abstract

“…Due to their structure, they have a large surface area, high adsorption capacity, and high selectivity, enabling the absorption of various components. ,− Consequently, they can provide an expanded surface area which facilitates particle and cell immobilization and attachment. Additionally, zeolites facilitate a suitable environment for encapsulation, enabling immobilized biomolecules to have enhanced stability, ensuring the material’s durability and functionality. Taking advantage of the above complementary properties of zeolite and graphene nanoparticles, we aim to use them as carriers for integrated cells.…”

Section: Introductionmentioning

confidence: 99%

Functionalizing the Electrical Properties of Kombucha Zoogleal Mats for Biosensing Applications

Nikolaidou,

Chiolerio,

Dehshibi

et al. 2024

ACS Omega

View full text Add to dashboard Cite

Kombucha is a type of tea that is fermented using yeast and bacteria. During this process, a film made of cellulose is produced. This film has unique properties such as biodegradability, flexibility, shape conformability, and ability to self-grow as well as be produced across customized scales. In our previous studies, we demonstrated that Kombucha mats exhibit electrical activity represented by spikes of the electrical potential. We propose using microbial fermentation as a method for in situ functionalization to modulate the electroactive nature of Kombucha cellulose mats, where graphene and zeolite were used for the functionalization. We subjected the pure and functionalized Kombucha mats to mechanical stimulation by applying different weights and geometries. Our experiments demonstrated that Kombucha mats functionalized with graphene and zeolite exhibit memfractive properties and respond to load by producing distinctive spiking patterns. Our findings present incredible opportunities for the in situ development of functionalized hybrid materials with sensing, computing, and memory capabilities. These materials can selfassemble and self-grow after they fuse their living and synthetic components. This study contributes to an emergent area of research on bioelectronic sensing and hybrid living materials, opening up exciting opportunities for use in smart wearables, diagnostics, health monitoring, and energy harvesting applications.

show abstract

Application of zeolites and zeolitic imidazolate frameworks in the biosensor development

Cited by 14 publications

References 50 publications

Natural Polymer Encapsulated Zeolitic Imidazolate Framework-12 Composite toward Electrochemical Sensing of Antitumor Agent

Natural Polymer Encapsulated Zeolitic Imidazolate Framework-12 Composite toward Electrochemical Sensing of Antitumor Agent

Electrochemical Wearable Biosensors and Bioelectronic Devices Based on Hydrogels: Mechanical Properties and Electrochemical Behavior

Functionalizing the Electrical Properties of Kombucha Zoogleal Mats for Biosensing Applications

Contact Info

Product

Resources

About