Application of α-adrenomimetic decongestants as chemical agents for gingival retraction

Abstract

Purpose: The purpose of this study is to observe, compare and evaluate the effect of two α-adrenomimetic decongestants which are clinically approved nasal and eye drops-0.05% xylometazoline hydrochloride and 0.05% tetrahydrozoline hydrochloride, when applied as chemical agents for chemo-mechanical retraction of free gingiva prior to impression making in fixed prosthodontics. Materials and methods: The study includes 90 prepared abutment teeth indicated for fixed prosthodontic treatment. α-adrenomimetic decongestants in the composition of 2 approved for clinical usage nasal and eye drops commercial products were applied as chemical agents for gingival retraction-Xylometazoline (0.05% xylometazoline hydrochloride) and Visine (0.05% tetrahydrozoline hydrochloride). Ultrapak retraction cord of four different sizes impregnated with the investigated chemical agents was used. Two steps twolayered impressions with polyvinyl and polydimethylsiloxane were taken from the prosthetic fields. Impression sections were fabricated and studied under microscope. Results: The low viscosity polyvinyl and polydimethyl siloxane layers tend to penetrate deeper in the gingival groove after chemo-mechanical retraction with Xylometazoline compared to the second group impressions fabricated after Visine retraction. Conclusion: The conducted testing demonstrated that effective retraction of the free marginal gingiva is possible to obtain with α-adernomimetic decongestants. 0.05% xylometazoline hydrochloride (Xylometazoline) provides better results in comparison to the eye decongestant drops 0.05% tеtrahydrozoline hydrochloride (Visine).

Conventional vs. digital impression technique for manufacturing of three-unit zirconia bridges: Evaluation of patients’ perception, preference, and treatment comfort

“…At the beginning of each clinical visit, a preparation of the abutment teeth was done, including: removal of the temporary restoration, cleaning of the prepared hard dental tissues from the temporary cement, and retraction of the soft tissues using two retraction cords (Ultrapak, Ultradent Products Inc., USA). ) and an impregnating agent from the group of α-adrenomimetic decongestants (xylometazoline 0.05%, Warsaw Pharmaceutical Works Polfa SA, Poland) in order to clearly visualize the preparation margin (13). In both impression techniques, impressions were taken separately for the upper and lower jaw, as well as occlusal registration.…”

Adequate gingival retraction as prerequisite for fabrication of precise fixed partial dentures – algorithm for clinical implementation

“…The analysis of the data shows higher efficiency of 0.05% xylometazoline HCl (Xylometazolin) in comparison to the ophthalmic decongestant 0.05% tetrahydrozoline HCl (Visine). Xylometazoline provides a thicker layer of impression material which penetrates deeper than half the gingival groove's depth (12)(13)(14). The results obtained from our previous researches, as well as the data gathered from the literature sources, demonstrate that α-adrenergic sympathicomimetic decongestants -0.05% xylometazoline HCl, 0.05% tetrahydrozoline HCl and 10% phenylephrine HCl, achieve sufficient hemostasis, adequate reduction of the crevice fluid and effective retraction of the free gingiva, respectively.…”

“…In search of the ideal chemical agent, researches revealed a new application for nasal and ophthalmic decongestantsoxymetazoline hydrochloride, xylometazoline hydrochloride, tetrahydrozoline hydrochloride, which belong to the group of α-adrenomimetic substances. It is proven that they lead to effective and reversible displacement of margo gingivalis without causing undesirable side effects on the oral and overall health of patients (11)(12)(13).…”