Applications and mechanisms of free and immobilized laccase in detoxification of phenolic compounds — A review

Rostami, Amin; Abdelrasoul, Amira; Shokri, Zahra; Shirvandi, Zeinab

doi:10.1007/s11814-021-0984-0

Cited by 22 publications

(6 citation statements)

References 76 publications

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“…As a result, laccase has been widely used in decontamination and restoration of hazardous chemical-contaminated waters [ 83 , 114 ]. The mechanisms of free and immobilized laccase in detoxification of phenolic compounds have been reviewed elsewhere [ 171 ].…”

Section: Applications Of Laccasementioning

confidence: 99%

Applications and immobilization strategies of the copper-centred laccase enzyme; a review

Kyomuhimbo¹,

Brink²

2023

Heliyon

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Section: Applications Of Laccasementioning

confidence: 99%

Applications and immobilization strategies of the copper-centred laccase enzyme; a review

Kyomuhimbo¹,

Brink²

2023

Heliyon

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“…The biological approach reduces, detoxifies, or mineralizes phenolic pollutants using microorganisms and their enzymes, such as laccase, and is also considered environmentally friendly. 1,2 Laccases are versatile multicopper oxidases that catalyze single-electron oxidation of a diverse array of substrates, including phenolic compounds such as polyphenols, amino-phenols, and polyamines. 2,3 They are widely distributed in nature and are mainly extracted from microorganisms, plants, and animals.…”

Section: Introductionmentioning

confidence: 99%

“…Therefore, mechanical, chemical, and biological methods have been employed to minimize or completely eliminate phenolic compounds. The biological approach reduces, detoxifies, or mineralizes phenolic pollutants using microorganisms and their enzymes, such as laccase, and is also considered environmentally friendly. , …”

Section: Introductionmentioning

confidence: 99%

Bacterial Nanocellulose/Copper as a Robust Laccase-Mimicking Bionanozyme for Catalytic Oxidation of Phenolic Pollutants

Achamyeleh,

Ankala,

Workie

et al. 2023

ACS Omega

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Industrial effluents containing phenolic compounds are a major public health concern and thus require effective and robust remediation technologies. Although laccase-like nanozymes are generally recognized as being catalytically efficient in oxidizing phenols, their support materials often lack resilience in harsh environments. Herein, bacterial nanocellulose (BNC) was introduced as a sustainable, strong, biocompatible, and environmentally friendly biopolymer for the synthesis of a laccase-like nanozyme (BNC/Cu). A native bacterial strain that produces nanocellulose was isolated from black tea broth fermented for 1 month. The isolate that produced BNC was identified as Bacillus sp. strain T15, and it can metabolize hexoses, sucrose, and less expensive substrates, such as molasses. Further, BNC/Cu nanozyme was synthesized using the in situ reduction of copper on the BNC. Characterization of the nanozyme by scanning electron microscopy (SEM) and X-ray diffraction (XRD) confirmed the presence of the copper nanoparticles dispersed in the layered sheets of BNC. The laccase-mimetic activity was assessed using the chromogenic redox reaction between 2,4-dichlorophenol (2,4-DP) and 4-aminoantipyrine (4-AP) with characteristic absorption at 510 nm. Remarkably, BNC/Cu has 50.69% higher catalytic activity than the pristine Cu NPs, indicating that BNC served as an effective biomatrix to disperse Cu NPs. Also, the bionanozyme showed the highest specificity toward 2,4-DP with a K m of 0.187 mM, which was lower than that of natural laccase. The bionanozyme retained catalytic activity across a wider temperature range with optimum activity at 85 °C, maintaining 38% laccase activity after 11 days and 46.77% activity after the fourth cycle. The BNC/Cu bionanozyme could efficiently oxidize more than 70% of 1,4-dichlorophenol and phenol in 5 h. Thereby, the BNC/Cu bionanozyme is described here as having an efficient ability to mimic laccase in the oxidation of phenolic compounds that are commonly released into the environment by industry.

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“…However, most of the proposed applications are still waiting to be used on a larger scale. In the last decade, the properties and uses of Lacs have been summarized in comprehensive reviews [ 17 , 18 , 19 ] and reviews focusing on subtopics such as applications of fungal Lacs [ 20 ], evolution and in vivo functions [ 5 ], biodegradation [ 21 , 22 , 23 , 24 ], biosensors [ 25 ], polymer synthesis [ 26 ] and grafting [ 27 ], biorefineries [ 28 ], food industry [ 29 ], wood composite production [ 30 ], immobilization [ 26 , 31 , 32 , 33 , 34 , 35 , 36 ], and biocatalysis in ionic liquids [ 37 ] or Lac mimics [ 38 ]. For background knowledge on Lac (structure, Lac-mediator reactions, applications) we refer to the review by Riva [ 1 ], and for an overview of laccases, their origin, and properties we refer to the review by Baldrian [ 39 ].…”

Section: Introductionmentioning

confidence: 99%

“…However, TYRs offer additional possibilities: In organic chemistry, they have been used to catalyze ortho -hydroxylations. They can also be useful in the modification of biopolymers [ 42 ] and biodegradation [ 21 ]. Most recent reviews on TYRs have focused on TYR inhibitors [ 43 , 44 , 45 , 46 , 47 , 48 , 49 ], which have been intensively studied because the enzyme plays a key role in melanogenesis.…”

Section: Introductionmentioning

confidence: 99%

Laccases and Tyrosinases in Organic Synthesis

Martı́nková

Křístková

Křen

2022

IJMS

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Laccases (Lac) and tyrosinases (TYR) are mild oxidants with a great potential in research and industry. In this work, we review recent advances in their use in organic synthesis. We summarize recent examples of Lac-catalyzed oxidation, homocoupling and heterocoupling, and TYR-catalyzed ortho-hydroxylation of phenols. We highlight the combination of Lac and TYR with other enzymes or chemical catalysts. We also point out the biological and pharmaceutical potential of the products, such as dimers of piceid, lignols, isorhamnetin, rutin, caffeic acid, 4-hydroxychalcones, thiols, hybrid antibiotics, benzimidazoles, benzothiazoles, pyrimidine derivatives, hydroxytyrosols, alkylcatechols, halocatechols, or dihydrocaffeoyl esters, etc. These products include radical scavengers; antibacterial, antiviral, and antitumor compounds; and building blocks for bioactive compounds and drugs. We summarize the available enzyme sources and discuss the scalability of their use in organic synthesis. In conclusion, we assume that the intensive use of laccases and tyrosinases in organic synthesis will yield new bioactive compounds and, in the long-term, reduce the environmental impact of industrial organic chemistry.

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Applications and mechanisms of free and immobilized laccase in detoxification of phenolic compounds — A review

Cited by 22 publications

References 76 publications

Applications and immobilization strategies of the copper-centred laccase enzyme; a review

Applications and immobilization strategies of the copper-centred laccase enzyme; a review

Bacterial Nanocellulose/Copper as a Robust Laccase-Mimicking Bionanozyme for Catalytic Oxidation of Phenolic Pollutants

Laccases and Tyrosinases in Organic Synthesis

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