Applications of AFM-IR for drug delivery vector characterization: infrared, thermal, and mechanical characterization at the nanoscale

Zhang, Jing; Khanal, Dipesh; Holl, Mark M. Banaszak

doi:10.1016/j.addr.2022.114646

Cited by 5 publications

(2 citation statements)

References 77 publications

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“…AFM has become an advantageous tool in the characterization of green MNPs designed for therapeutic applications in the biomedical field, where nanoparticles offer enormous potential. AFM structural details provide insights into the interactions of NPs with biological entities, helping in the development of targeted drug delivery systems or agents for imaging [370]. The versatile nature of AFM is further demonstrated while investigating the physical characteristics of mechanical qualities like as elasticity, stiffness, and adhesion.…”

Section: Transmission Electron Microscopmentioning

confidence: 99%

Breaking Barriers in Eco-Friendly Synthesis of Plant-Mediated Metal/Metal Oxide/Bimetallic Nanoparticles: Antibacterial, Anticancer, Mechanism Elucidation, and Versatile Utilizations

Dubey,

Virmani,

Yadav

et al. 2024

Journal of Nanomaterials

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Nanotechnology has emerged as a promising field in pharmaceutical research, involving producing unique nanoscale materials with sizes up to 100 nm via physiochemical and biological approaches. Nowadays more emphasis has been given to eco-friendly techniques for developing nanomaterials to enhance their biological applications and minimize health and environmental risks. With the help of green nanotechnology, a wide range of green metal, metal oxide, and bimetallic nanoparticles with distinct chemical compositions, sizes, and morphologies have been manufactured which are safe, economical, and environment friendly. Due to their biocompatibility and vast potential in biomedical (antibacterial, anticancer, antiviral, analgesic, anticoagulant, biofilm inhibitory activity) and in other fields such as (nanofertilizers, fermentative, food, and bioethanol production, construction field), green metal nanoparticles have garnered significant interest worldwide. The metal precursors combined with natural extracts such as plants, algae, fungi, and bacteria to get potent novel metal, metal oxide, and bimetallic nanoparticles such as Ag, Au, Co, Cu, Fe, Zr, Zn, Ni, Pt, Mg, Ti, Pd, Cd, Bi2O3, CeO2, Co3O4, CoFe2O4, CuO, Fe2O3, MgO, NiO, TiO2, ZnO, ZrO2, Ag-Au, Ag-Cr, Ag-Cu, Ag-Zn, Ag-CeO2, Ag-CuO, Ag-SeO2, Ag-TiO2, Ag-ZnO, Cu-Ag, Cu-Mg, Cu-Ni, Pd-Pt, Pt-Ag, ZnO-CuO, ZnO-SeO, ZnO-Se, Se-Zr, and Co-Bi2O3. These plant-mediated green nanoparticles possess excellent antibacterial and anticancer activity when tested against several microorganisms and cancer cell lines. Plants contain essential phytoconstituents (polyphenols, flavonoids, terpenoids, glycosides, alkaloids, etc.) compared to other natural sources (bacteria, fungi, and algae) in higher concentration that play a vital role in the development of green metal, metal oxide, and bimetallic nanoparticles because these plant-phytoconstituents act as a reducing, stabilizing, and capping agent and helps in the development of green nanoparticles. After concluding all these findings, this review has been designed for the first time in such a way that it imparts satisfactory knowledge about the antibacterial and anticancer activity of plant-mediated green metal, metal oxide, and bimetallic nanoparticles together, along with antibacterial and anticancer mechanisms. Additionally, it provides information about characterization techniques (UV–vis, FT-IR, DLS, XRD, SEM, TEM, BET, AFM) employed for plant-mediated nanoparticles, biomedical applications, and their role in other industries. Hence, this review provides information about the antibacterial and anticancer activity of various types of plant-mediated green metal, metal oxide, and bimetallic nanoparticles and their versatile application in diverse fields which is not covered in other pieces of literature.

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Section: Transmission Electron Microscopmentioning

confidence: 99%

Breaking Barriers in Eco-Friendly Synthesis of Plant-Mediated Metal/Metal Oxide/Bimetallic Nanoparticles: Antibacterial, Anticancer, Mechanism Elucidation, and Versatile Utilizations

Dubey,

Virmani,

Yadav

et al. 2024

Journal of Nanomaterials

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“…Therefore, the electron-beam/electric multiplexing memory based on domain-controllable strategies serves as a new type of high-security-level information encryption, except for optical storage material (OSM). 28 Meanwhile, the effect of the exposure dose on domain evolutions from the relaxor ferroelectric phase into the paraelectric phase and dipole orientations were confirmed by atomic force microscopy-infrared spectroscopy 29 (AFM-IR) and piezoelectric force microscopy (PFM). 30 Briefly, our systematic study paves a new avenue to develop high-density ferroelectric patterns for high-security-level information storage and encryption, which has emerged as the next-generation memory devices.…”

Section: Introductionmentioning

confidence: 95%

Electron-beam writing of a relaxor ferroelectric polymer for multiplexing information storage and encryption

Li,

Chen,

Fang

et al. 2024

Nanoscale

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Nanoscale colocalized thermal and chemical mapping of pharmaceutical powder aerosols

Zhang,

Khanal,

Chan

et al. 2024

International Journal of Pharmaceutics

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Applications of AFM-IR for drug delivery vector characterization: infrared, thermal, and mechanical characterization at the nanoscale

Cited by 5 publications

References 77 publications

Breaking Barriers in Eco-Friendly Synthesis of Plant-Mediated Metal/Metal Oxide/Bimetallic Nanoparticles: Antibacterial, Anticancer, Mechanism Elucidation, and Versatile Utilizations

Breaking Barriers in Eco-Friendly Synthesis of Plant-Mediated Metal/Metal Oxide/Bimetallic Nanoparticles: Antibacterial, Anticancer, Mechanism Elucidation, and Versatile Utilizations

Electron-beam writing of a relaxor ferroelectric polymer for multiplexing information storage and encryption

Nanoscale colocalized thermal and chemical mapping of pharmaceutical powder aerosols

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