Applications of CFD Technique in the Design and Flow Analysis of Implantable Axial Flow Blood Pump

Fan, Huimin; Hong, Fang-wen; Zhang, Guoping; Liang, Y. T.; Liu, Zhongmin

doi:10.1016/s1001-6058(09)60084-6

Cited by 20 publications

(9 citation statements)

References 5 publications

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“…[2][3][4][5][6] Because of the high rotational speeds of pumps, blood cells may pass through the pump without excessive deformation or hemolytic damage. Many studies, however, only pertain to the blood flow inside the heart pumps.…”

mentioning

confidence: 99%

Effect of LVAD Outlet Graft Anastomosis Angle on the Aortic Valve, Wall, and Flow

Inci

Sorgüven

2012

ASAIO Journal

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Left ventricular assist devices (LVADs), which pump blood from the left ventricle to the aorta are an important therapy option for patients with end-stage cardiovascular diseases. Recent publications show that even with optimized LVADs fatal complications can occur because of the blood deformations around the inflow cannula or through the LVAD outlet graft-aorta anastomosis. This study investigates the effects of the anastomosis geometry on the flow through the aorta, on the pressure and wall shear stress (WSS) distributions on the aortic wall and on the total entropy generation in the anastomosis region. Anastomosis geometry is defined with two angles, one on the coronal plane and the other on the transversal plane. Turbulent flow simulations are performed for each geometry. Results indicate that 3% to 5% of the work given by the LVAD is dissipated because of the viscous losses in the anastomosis region. The entropy generation, as well as the maximum WSS, increases as the inclination angle decreases. Some portion of the blood streaming out of the LVAD conduit flows toward the aortic valve; therefore the reverse-flow region extends up to the aortic valve in some cases, which may be one of the causes of aortic-valve dysfunction. Results of this study provide insight on the importance of the anastomosis geometry on the hemodynamics in the aorta and downstream the aortic valve, stresses on the aortic wall, and viscous losses.

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mentioning

confidence: 99%

Effect of LVAD Outlet Graft Anastomosis Angle on the Aortic Valve, Wall, and Flow

Inci

Sorgüven

2012

ASAIO Journal

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“…Continuous-flow cardiac assist pumps have been successfully used to treat end-stage heart failure patients as destination therapy, bridge-to-transplantation or bridgeto-recovery [1][2][3]. However, hemolysis reduction is still a significant design challenge for blood pumps [2,3].…”

Section: Introductionmentioning

confidence: 99%

Numerical investigation of volute tongue design on hemodynamic characteristics and hemolysis of the centrifugal blood pump

2021

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In the design of rotary blood pumps, the optimization of design parameters plays an essential role in enhancing the hydrodynamic performance and hemocompatibility. This study investigates the influence of the volute tongue angle as a volute geometric parameter on the hemodynamic characteristics of a blood pump. A numerical investigation on five different versions of volute designs is carried out by utilizing a computational fluid dynamics (CFD) software ANSYS-FLUENT. The effect of volute tongue angle is evaluated regarding the hydrodynamic performance, circumferential pressure distribution, the radial force, and the blood damage potential. A series of volute configurations are constructed with a fixed radial gap (5%), but varying tongue angles ranging from 10 to 50°. The relative hemolysis is assessed with the Eulerian based empirical power-law blood damage model. The pressure-flow rate characteristics of the volute designs at a range of rotational speeds are obtained from the experimental measurements by using the blood analog fluid. The results indicate an inverse relationship between hydraulic performance and the tongue angle; at higher tongue angles, a decrease in performance was observed. However, a higher tongue angle improves the net radial force acting on the impeller. The pump achieves the optimized performance at 20° of the tongue angle with the relatively high hydrodynamic performance and minor blood damage risk.

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“…With the development of heart surgery, VADs have been used as a bridge-to-transplant or destination therapy [1][2][3]. The VAD provides effective blood circulation support until a donor heart becomes available for transplant, improves other organ function, improves exercise performance, and enables participation in cardiac rehabilitation [4].…”

Section: Introductionmentioning

confidence: 99%

“…Rotary pumps are designed to work in a constant speed mode of mechanical circulatory support, thus, in principle, produce non-pulsatile flow. Compared with displacement pumps, the rotary type pumps have advantages of compactness, no valves, simpler control aspects, lower power consumption, lower relative cost, and a more simplistic design, which results in smaller size and increased reliability [2,8,10]. However, the fluid dynamic forces in centrifugal blood pump impellers contribute to the destruction of red blood cells because the rotational speed leads to harsh interactions between the impeller and red blood cells [11][12][13].…”

Section: Introductionmentioning

confidence: 99%

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Improved Hemolytic Performance of Blood Pump with Fluorine-Doped Hydrogenated Amorphous Carbon Coating

Ohgoe

Hiratsuka²,

Sumikura³

et al. 2013

ACES

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Fluorine-doped hydrogenated amorphous carbon (a-C:H:F) film was deposited on a flow-straightener, impeller and diffuser surface (SUS 304) of an enclosed-impeller type flow blood pump using the ionization deposition method with a source gas of C₆F₅H. The surface characteristics of the a-C:H:F film were examined using atomic force microscopy, X-ray photoelectron spectroscopy, and measurements of surface roughness, friction and surface potential. The a-C:H:F film tends to increase surface roughness and the negative surface charge. In addition, the surface energy and friction decrease with fluorine dopant in the a-C:H film. To estimate the hemolytic performance of a blood pump with the a-C:H:F film coating, the amount of hemolysis was measured using a mock circulatory system (in vitro test) with 500 mL of pig blood containing sodium citrate. In vitro test was conducted for 180 min with the blood flow and pump head maintained at 5 L/min and 100 mmHg, respectively. The a-C:H:F film coating reduced the amount of hemolysis and improved the hemolytic performance. Decreasing the surface energy and negative surface charge of the a-C:H:F film contributes to the improvement of the hemolytic performance. The a-C:H:F film coating is thus expected to be utilized in medical technology as a surface coating technology for artificial heart blood pumps.

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Applications of CFD Technique in the Design and Flow Analysis of Implantable Axial Flow Blood Pump

Cited by 20 publications

References 5 publications

Effect of LVAD Outlet Graft Anastomosis Angle on the Aortic Valve, Wall, and Flow

Effect of LVAD Outlet Graft Anastomosis Angle on the Aortic Valve, Wall, and Flow

Numerical investigation of volute tongue design on hemodynamic characteristics and hemolysis of the centrifugal blood pump

Improved Hemolytic Performance of Blood Pump with Fluorine-Doped Hydrogenated Amorphous Carbon Coating

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