Applications of laser-polarized129Xe under continuous flow

Variable Temperature Study of the Cross-Relaxation Dynamics in the Hyperpolarized Xenon-Induced Enhancement of Surface Nuclei

“…Optical pumping of 129 Xe and 3 He creates spin polarizations that are 4 to 5 orders of magnitude higher than thermal polarization. [14][15][16] The large gain in polarization and thus signal intensity has created opportunities in a range of fields including medical imaging, physics, and materials science. [17][18][19][20][21][22][23][24][25][26][27] To combine the enhanced signals of the hyperpolarized noble gases with the elemental selectivity of NMR, efforts have been made to transfer the high noble gas polarization to other nuclei.…”

Hyperpolarised xenon MRI and time-resolved X-ray computed tomography studies of structure-transport relationships in hierarchical porous media

“…Second, for the mass transport imaging measurements, hp 129 Xe was produced in continuous flow mode. The major difference with the first method is that the outlet of the SEOP cell is opened, and the inlet also remains open, thus providing a constant flow of gas which is polarised in stream [42]. The flow of gas in this mode was controlled using two needle valves, located before and after the sample.…”

Hyperpolarized xenon in NMR and MRI

“…The subject of polarization transfer from polarized xenon to other nuclei is the exclusive subject of one excellent review (Song 2000) and an important part of a few excellent others (Pietraß 1999, Brunner 1999a, 1999b, Goodson 2002. We discuss it only briefly in the following, with focus on SPINOE and thermal mixing.…”

“…The main field of application of 3 He, besides polarized targets for nuclear and particle physics, is lung imaging; for relevant reviews see section 1. The production of polarization was reviewed by Happer (1972) and Walker and Happer (1997); several reviews are dedicated to NMR spectroscopy with laser polarized xenon with application to surface studies , Pietraß 1999, Brunner 1999a) and biological systems (Brunner 1999b, Goodson 2002; one review concentrates on polarization transfer from hyperpolarized xenon (Song 2000); aspects related to the delivery of polarized xenon to biological systems can be found in Goodson (1999); imaging of a variety of systems, with emphasis on living organisms, has been reviewed in Albert and Balamore (1998), Bifone et al (1999), Chupp and Swanson (2001), Mugler et al (2004a) and on low-field imaging in Mair and Walsworth (2002).…”