Applications of Natural Products in Food

González‐Manzano, Susana; Dueñas, Montserrat

doi:10.3390/foods10020300

Cited by 13 publications

(11 citation statements)

References 12 publications

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“…In the food industry, using natural preservatives may reduce the quality of food and make the food organoleptically unacceptable [ 104 ]. The concentration of active compounds greater than the threshold level increases the efficacy loss of food components that alter sensory properties such as taste and smell [ 105 ]. Furthermore, spices could provoke intense or pungent aromas in the food.…”

Section: Natural Products As a Promising Alternatementioning

confidence: 99%

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Exploring Possible Ways to Enhance the Potential and Use of Natural Products through Nanotechnology in the Battle against Biofilms of Foodborne Bacterial Pathogens

Kannappan

Prasath²,

Sathya

et al. 2023

Pathogens

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Biofilms enable pathogenic bacteria to survive in unfavorable environments. As biofilm-forming pathogens can cause rapid food spoilage and recurrent infections in humans, especially their presence in the food industry is problematic. Using chemical disinfectants in the food industry to prevent biofilm formation raises serious health concerns. Further, the ability of biofilm-forming bacterial pathogens to tolerate disinfection procedures questions the traditional treatment methods. Thus, there is a dire need for alternative treatment options targeting bacterial pathogens, especially biofilms. As clean-label products without carcinogenic and hazardous potential, natural compounds with growth and biofilm-inhibiting and biofilm-eradicating potentials have gained popularity as natural preservatives in the food industry. However, the use of these natural preservatives in the food industry is restricted by their poor availability, stability during food processing and storage. Also there is a lack of standardization, and unattractive organoleptic qualities. Nanotechnology is one way to get around these limitations and as well as the use of underutilized bioactives. The use of nanotechnology has several advantages including traversing the biofilm matrix, targeted drug delivery, controlled release, and enhanced bioavailability, bioactivity, and stability. The nanoparticles used in fabricating or encapsulating natural products are considered as an appealing antibiofilm strategy since the nanoparticles enhance the activity of the natural products against biofilms of foodborne bacterial pathogens. Hence, this literature review is intended to provide a comprehensive analysis of the current methods in nanotechnology used for natural products delivery (biofabrication, encapsulation, and nanoemulsion) and also discuss the different promising strategies employed in the recent and past to enhance the inhibition and eradication of foodborne bacterial biofilms.

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Section: Natural Products As a Promising Alternatementioning

confidence: 99%

“…Furthermore, spices could provoke intense or pungent aromas in the food. In addition, the storage temperature and heating processes (sterilization and dehydration) are essential factors that induce the active compounds to lose their respective inhibitory activities [ 105 , 106 ].…”

Section: Natural Products As a Promising Alternatementioning

confidence: 99%

Exploring Possible Ways to Enhance the Potential and Use of Natural Products through Nanotechnology in the Battle against Biofilms of Foodborne Bacterial Pathogens

Kannappan

Prasath²,

Sathya

et al. 2023

Pathogens

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“…This natural diversity has in turn been leveraged for wide-ranging applications to benefit human society. Some examples include agricultural pesticides to increase food production, 3 food preservatives to facilitate distribution and storage, 4,5 and most prominently therapeutic agents to treat diseases. [6][7][8] Indeed, it has been estimated that approximately 80% of all clinically used antibiotics can have its origins traced to a natural product.…”

Section: Background and Summarymentioning

confidence: 99%

68 million natural product-like compound database generated via molecular language processing

Tay

Adaikkappan

et al. 2023

Preprint

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Natural products are a rich resource of bioactive compounds for valuable applications across multiple fields such as food, agriculture, medicine. For natural product discovery, high throughput in silico screening offers a cost-effective alternative to traditional resource-heavy assay-guided exploration of structurally novel chemical space. In this data descriptor, we report a characterized database of 68,113,839 natural product-like molecules generated using a recurrent neural network trained on known natural products, demonstrating a significant 167-fold expansion in library size over the currently estimated 406,919 natural products known. This study highlights the potential of using deep generative models to uncover novel natural product chemical space for high throughput in silico screening toward natural product discovery.

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“…1 Recently, the worldwide demand for natural extracts, particularly those originated from plant by-products, has been growing continuously. These extracts can potentially be used in food preservation, 2 food additives, 3 pharmaceuticals, 4 and cosmetics. 5 Flowers are believed to contain various nutritional and bioactive components, having a long history of consumption as healthy foods.…”

Section: Introductionmentioning

confidence: 99%

“…Recently, the worldwide demand for natural extracts, particularly those originated from plant by‐products, has been growing continuously. These extracts can potentially be used in food preservation, 2 food additives, 3 pharmaceuticals, 4 and cosmetics 5 …”

Section: Introductionmentioning

confidence: 99%

Comparison of the effect of extraction methods on waste cotton (Gossypium hirsutum L.) flowers: metabolic profile, bioactive components, antioxidant, and α‐amylase inhibition

Dong

Peng

et al. 2023

J Sci Food Agric

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BACKGROUNDWaste cotton flowers, as a by‐product of cotton cultivation, are enriched with bioactive substances that render them a promising natural source of health‐promoting benefits. In this study, ultrasound‐assisted extraction (UAE), subcritical water extraction (SWE), and conventional extraction (CE) approaches were applied to extract bioactive compounds from waste cotton flowers, and the metabolic profiles, bioactive components, antioxidants, and α‐amylase inhibition of different extractions were systematically analyzed and compared.RESULTSIt was observed that UAE and CE extracts had similar metabolic profiles compared with SWE. The flavonoids and amino acids and derivatives were more prone to be extracted by UAE and CE, whereas phenolic acids tended to accumulate in SWE extract. The UAE extract had the highest amounts of total polyphenols (214.07 mg gallic acid equivalents per gram dry weight) and flavonoids (33.23 mg rutin equivalents per gram dry weight) as well as the strongest inhibition on oxidation (IC50 = 10.80 μg mL−1) and α‐amylase activity (IC50 = 0.62 mg mL−1), indicating that chemical composition was closely related to biological activity. Additionally, microstructures and thermal behaviors of the extracts were investigated and highlighted the ability of UAE.CONCLUSIONOverall, it can be concluded that UAE is an efficient, green, and economical extraction method to produce bioactive compounds from cotton flowers, and the UAE extracts could be used in food and medicine industries because of their high antioxidant and α‐amylase inhibitory activity. This study provides a scientific basis for the development and comprehensive utilization of cotton by‐products. © 2023 Society of Chemical Industry.

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Applications of Natural Products in Food

Abstract: The term natural products includes any substance produced by living organisms [...]

Cited by 13 publications

References 12 publications

Exploring Possible Ways to Enhance the Potential and Use of Natural Products through Nanotechnology in the Battle against Biofilms of Foodborne Bacterial Pathogens

Exploring Possible Ways to Enhance the Potential and Use of Natural Products through Nanotechnology in the Battle against Biofilms of Foodborne Bacterial Pathogens

68 million natural product-like compound database generated via molecular language processing

Comparison of the effect of extraction methods on waste cotton (Gossypium hirsutum L.) flowers: metabolic profile, bioactive components, antioxidant, and α‐amylase inhibition

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