Applications of Nitrile Imine Derivatives

Jamieson, Craig; Livingstone, Keith

doi:10.1007/978-3-030-43481-6_4

Cited by 1 publication

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References 151 publications

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“…Although the majority of the literature focuses on their role in 1,3-dipolar cycloadditions, it has been demonstrated that they can also react with a variety of nucleophiles, including alcohols, amines, and carboxylic acids, to give dimerization reactions, intramolecular rearrangements, and other transformations. [9] Since NIs are unstable, they are typically generated in situ using an appropriate precursor. The most common precursors are hydrazonyl halides [10] and 2,5tetrazoles [11] (Scheme 1), but more modern approaches have also been discovered.…”

Section: Nitrile Imines As 13-dipolesmentioning

confidence: 99%

Strategies and Methods for the Synthesis of 2‐Pyrazolines: Recent Developments (2012–2022)

Matiadis

2023

Adv Synth Catal

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2‐Pyrazolines are important five‐membered heterocycles, containing two adjacent nitrogen atoms. They can incorporate various functional groups and possess unique biological properties. Moreover, they have been used as useful building blocks. In recent years, the field of 2‐pyrazoline synthesis has experienced enormous progress. Novel strategies have been developed, and many studies reporting improvements or adaptations of existing protocols have been published, giving access to new functionalizations, unexplored structures, and/or enantioselective synthesis. This review summarizes the progress made in synthetic methodologies during the period from 2012 to 2022. The functionalization challenges and capabilities, scopes and limitations of the reactions, substitution patterns, and mechanisms of the reactions, where appropriate, will be discussed.

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Section: Nitrile Imines As 13-dipolesmentioning

confidence: 99%

Strategies and Methods for the Synthesis of 2‐Pyrazolines: Recent Developments (2012–2022)

Matiadis

2023

Adv Synth Catal

View full text Add to dashboard Cite

show abstract

Applications of Nitrile Imine Derivatives

Cited by 1 publication

References 151 publications

Strategies and Methods for the Synthesis of 2‐Pyrazolines: Recent Developments (2012–2022)

Strategies and Methods for the Synthesis of 2‐Pyrazolines: Recent Developments (2012–2022)

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