Applications of Shape Memory Alloys for Neurology and Neuromuscular Rehabilitation

Pittaccio, Simone; Garavaglia, Lorenzo; Ceriotti, Carlo; Passaretti, Francesca

doi:10.3390/jfb6020328

Cited by 36 publications

(28 citation statements)

References 31 publications

(43 reference statements)

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“…In another study [32,33], Pittacio et al designed and fabricated a specific hinge containing NiTi to transfer the pseudoelastic recovery force to fitted splints in the elbow joint. The pseudoelastic hinge presented in this paper (Figure 11) is composed of two parts which are able to rotate relative to one another around a common central axis.…”

Section: Smas In Assistive Devicesmentioning

confidence: 99%

Application of NiTi in Assistive and Rehabilitation Devices: A Review

et al. 2019

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Shape memory alloys (SMAs) have found widespread applications as biomedical devices. Biocompatibility, corrosion resistance, and ductility make these alloys attractive for medical devices such as stents and filters. For these implants, the superelastic property is the primary function of SMAs. Additionally, these alloys, such as NiTi as the prime example, can be used for actuation. Several modes of actuation such as displacement control, force control, and compliance control have been used as harnesses with SMA devices. These two unique properties have opened another application in the form of neurosurgery and robot-assisted surgery devices, as well as controlled assistive and rehabilitation devices. This paper reviews the state of the art of application of SMAs in the latter category where control is applied to harness innovative medical devices. To this end, two major subsets of these devices: prosthesis and orthosis which take the advantage of SMAs in assistive and rehabilitation devices are studied. These devices are further categorized to hand prosthetics, elbow, knee and ankle orthotics. In most of these designs, SMA wires act as artificial muscles to mimic the motion of limbs in the target joints. The evolution of each category is explained, and the specific results of them are reported. The paper also reviews the SMA applications for neurological and neuromuscular rehabilitation. To this end, different categories of rehabilitation devices as a passive and aided exercise for the ankle, knee, and elbow are highlighted. The SMA actuator in these devices can be EMG-controlled to improved patient outcome. In addition to providing a comprehensive overview of the biomedical devices, this paper identifies several possible future directions of SMA related research in the area of assistive and rehabilitation devices.

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Section: Smas In Assistive Devicesmentioning

confidence: 99%

Application of NiTi in Assistive and Rehabilitation Devices: A Review

et al. 2019

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“…In the bones of the young and most of the adult, all these functionalities appear, so that when an accident requires a human operation it is good to resort to mild and specialized interventions so that the bone in question can quickly recover all features. Otherwise, the body of that person has a major future health and integrity problem, as is the case with older people or those with serious bone diseases (Roger, 2015;Benchea et al, 1976;McCracken et al, 2000;Pittaccio et al, 2015;Viscuso and Pittaccio, 2012;Priadko et al, 2017;Nikolaev et al, 2008;Yang et al, 2013;Van Humbeeck, 2010;Otsuka and Ren, 1999;Otsuka et al, 1971;Velázquez and Pissaloux, 2012;Melton and Mercier, 1980;Knowles and Smith, 1981;Miyazaki et al, 1984;Lahoz and Puértolas, 2004;Matsumoto et al, 1987;Šittner et al, 2014;Duerig, 1990;Naresh et al 2016;Ziólkowski, 2012;Shaw et al, 2008;Aversa et al, 2018;a-c, 2016Mirsayar et al, 2017;Petrescu et al, 2015, 2016 a-c; Petrescu and Calautit, 2016 a-b; Kus and Breczko, 2010;Otsuka et al, 1976, Yang andb 1992;Harrison and Hodgson, 1975;Hanlon et al, 1967;Huang et al, 2003;Sofla et al, 2008;Tamburrino, 2016;Apicella et al, -20112015;Gramanzini et al, 2016;Kummer, 1986;…”

Section: Physiology Of the Bone Systemmentioning

confidence: 99%

Mechanically Stimulated Osteoblast Cells Growth

Aversa¹,

Apicella²,

Tamburrino³

et al. 2018

American Journal of Engineering and Applied Sciences

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The bones need to be built and then permanently restored to keep them functioning properly. Considering the multiple bone functions, their vitality is essential both to maintain the body and move it and to maintain its health and vigor. When most bones begin to age and have no vital function, the man also begins to age, lose water, minerals, electrolytes, energy, food. We can firmly affirm that healthy bones maintain an excellent health of the human body. All of the bones in the young have the role of deposit, water, electrolyte, minerals, energy, substances necessary for the growth and repair of human cells and organs, a part (red marrow) that permanently produces the vital blood for the organism with the three vital cell types: red (body oxygenation), white (which defends the body) and platelets (it clogs the blood when a wound appears). More recently, it is also known that the red marrow is responsible for the stem cells production, cells which are so necessary to the body because they can adapt to anywhere in the body in any organ, rapidly generating the various types of cells needed. In the bones of the young and most of the adult, all these functionalities appear, so that when an accident requires a human operation it is good to resort to mild and specialized interventions so that the bone in question can quickly recover all features. Otherwise, the body of that person has a major future health and integrity problem, as is the case with older people or those with serious bone diseases. The research develops and tests new hybrid biomimetic materials that work as mechanically stimulating "scaffolds" to promote early regeneration in implanted bone healing phases. A biomimetic nanostructured osteoconductive material coated apparatus is presented. Bioinspired approaches to materials and templated growth of hybrid networks using self-assembled hybrid organicinorganic interfaces are finalized to extend the use of hybrids in the medical field. Combined in vivo, in vitro and computer-aided simulations have been carried out. Such multidisciplinary approach allowed us to explore many novel ideas in modeling, design and fabrication of new nanostructured biomaterials and scaffolds with enhanced functionality and improved interaction with OB cells. In vivo tests of Titanium screw implanted in rabbit, tibiae have shown that mechanical stimulation was induced by the presence of bioactive hybrid perimplantar scaffold resulting in a differentiation and development of mesenchymal tissues. In order to investigate the relationship between bone growth and applied mechanical loading (strain), a piezoelectrically driven cantilever and a computercontrolled apparatus for "in vitro" tests has been developed and presented.

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“…With the wires, programmed to have a two-way memory effect, using milling and additive technologies, prototypes where the wires are embedded in casted polymers (rubber silicone or polyurethane) or assembled to parts manufactured with additive technologies have been built, in order to test and enhance product functioning and manufacturability (Pittaccio et al, 2015;Viscuso and Pittaccio, 2012;Priadko et al, 2017;Nikolaev et al, 2008;Yang et al, 2013;Yang and Wayman, 1992;Van Humbeeck, 2010;Otsuka and Ren, 1999;Otsuka et al, 1971;Velázquez and Pissaloux, 2012;Melton and Mercier, 1980;Knowles and Smith, 1981;Miyazaki et al, 1984;Lahoz and Puértolas, 2004;Matsumoto et al, 1987;Šittner et al, 2014;Duerig, 1990;Naresh et al, 2016;Ziólkowski, 2012;Shaw et al, 2008;Aversa et al, 2018;2017a;2017b;2017c;2016d;2016e;2016f;2016g;2016h;2016i;Mirsayar et al, 2017;Petrescu et al, 2015Petrescu and Calautit, 2016a;Kus and Breczko, 2010;Otsuka et al 1976;Yang and Wayman, 1992;Harrison, 1975;Hanlon, 1967;…”

Section: Introductionmentioning

confidence: 99%

Advanced Manufacturing for Novel Materials in Industrial Design Applications

Tamburrino¹,

Apicella²,

Aversa³

et al. 2018

American Journal of Engineering and Applied Sciences

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Abstract:The research presented starts with a focus on Smart Materials, or rather materials with properties that react to external stimuli (temperature, electric or magnetic field, pH or mechanical stress, for example) related to the environmental changes, modifying one or some of their own properties (mechanical, electrical, appearance, etc.). Afterward, one category of Smart Materials, Shape Memory Alloys (SMAs), has been investigated with the aim to develop an industrial application. In particular, a smart and active shadow system for thermal comfort of urban or indoor environments, based on the valorization of the unique property of SMAs to change their shape depending on the temperature (SME, Shape Memory Effect). Without the need to use expensive and complex mechanical system composed of many parts to assemble and characterized by higher cost of energy required for its functioning and its manufacturing. In order to develop the system, SMAs like Nitinol (Ni-Ti) wires with a diameter of 0,75 mm (Austenite finish 85°C) have been studied. Particularly, DSC (Differential Scanning Calorimetry) thermal analysis, aimed to investigate a characteristic range of temperature for martensitic and austenitic transformations and get data to plan more suitable and optimized procedures, conditions and parameters for heat treatments needed for Nitinol training have been carried out. In parallel, CAD models have been developed to simulate and better understand forces needed for a proper functioning of the smart shadow system, to predict its behavior, to have a support for a correct choice of SMA wires (selecting wires with a diameter suitable to produce a force high enough to produce strains), to decide wires positioning and quantity. Finally, for "as-drawn" Nitinol wires, using the data experimentally collected with DSC thermal analysis, SME training procedures have experimented. With the wires, programmed to have a two-way memory effect, using milling and additive technologies, prototypes where the wires are embedded in casted polymers (rubber silicone or polyurethane) or assembled to parts manufactured with additive technologies have been built, in order to test and enhance product functioning and manufacturability. The results obtained for the application, although the Smart Shadow System is not completely engineered and other evolutionary steps for it are possible, show that the use of SMAs gives the possibility to have an active system able to be weather responsive, ensuring a significant shape memory effect depending on the temperature. This advanced property, in fact, gives the possibility, optimizing functioning parameters (temperatures, thicknesses, geometry, structure), to have a sensitive, adaptive and smart system that can ensure the best thermal condition for any meteorological situation.

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Applications of Shape Memory Alloys for Neurology and Neuromuscular Rehabilitation

Cited by 36 publications

References 31 publications

Application of NiTi in Assistive and Rehabilitation Devices: A Review

Application of NiTi in Assistive and Rehabilitation Devices: A Review

Mechanically Stimulated Osteoblast Cells Growth

Advanced Manufacturing for Novel Materials in Industrial Design Applications

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