Applications of ultrasound in total synthesis of bioactive natural products: A promising green tool

Abstract

Graphical abstract

Recent developments using malononitrile in ultrasound-assisted multicomponent synthesis of heterocycles

“…Ultrasound irradiation stands as an influential and environmentally amicable technique capable of augmenting multicomponent reactions (MCRs) through furnishing heat, agitation, activation, or synergism [17] , [18] . The assimilation of ultrasound-assisted methodologies within multicomponent syntheses has, of late, piqued interest among the chemical scholarly circles.…”

Samarium(III) Triflate in Organic Synthesis: a Mild and Efficient Catalyst

“…[10,11] Besides, catalysis is a potential synthetic tool for the synthesis of promising organic molecules as well as the total synthesis of bioactive secondary metabolites for accomplishing a high degree of molecular complexity from comparatively simple building blocks. [12][13][14][15][16][17][18][19][20][21][22] Triflate salts of the lanthanides, commonly known as lanthanide triflate, have been examined for their application in the synthesis of organic molecules as a water-tolerant Lewis acid. [23] Lanthanides display variable oxidation states such as + 2, + 3, and + 4 oxidation states.…”

Characterization and Exploration of the Neuroprotective Potential of Oat-Protein-Derived Peptides in PC12 Cells and Scopolamine-Treated Zebrafish

“…Generally, hydrolysates or peptides with bioactive properties are obtained by the enzymatic hydrolysis of proteins. Ultrasonic processing has gained attention as an eco-friendly, cost-effective, and safe method for extracting natural substances [ 20 ]. The use of ultrasonics enhances the preparation and activity of bioactive peptides by altering protein structure and exposing cleavage sites, enabling the efficient development of protein resources and facilitating the production of bioactive peptides [ 21 ].…”