Applications of vitamin B6 cofactor pyridoxal 5′-phosphate and pyridoxal 5′-phosphate crowned gold nanoparticles for optical sensing of metal ions

Bothra, Shilpa; Upadhyay, Yachana; Kumar, Rajender; Sahoo, Suban K.

doi:10.1016/j.saa.2016.11.014

Cited by 25 publications

(10 citation statements)

References 40 publications

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“…Aluminum is the third most abundant metal in Earth’s crust and has found wide applications in household devices, building materials, transportation, electronics, and sophisticated medical devices . Courtesy of its extensive use in daily life, aluminum also has very high exposure .…”

Section: Introductionmentioning

confidence: 99%

Turn-On Fluorescent Sensors for the Selective Detection of Al³⁺ (and Ga³⁺) and PPi Ions

Kumar

et al. 2019

Inorg. Chem.

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Rationally designed multiple hydroxyl-group-based chemosensors L1–L4 containing arene-based fluorophores are presented for the selective detection of Al3+ and Ga3+ ions. Changes in the absorption and emission spectra of L1–L4 in ethanol were easily observable upon the addition of Al3+ and Ga3+ ions. Competitive binding studies, detection limits, and binding constants illustrate significant sensing abilities of these chemosensors with L4, showing the best results. The interaction of Al3+/Ga3+ ions with chemosensor L4 was investigated by fluorescence lifetime measurements, whereas Job’s plot, high-resolution mass spectrometry, and 1H NMR spectral titrations substantiated the stoichiometry between L4 and Al3+/Ga3+ ions. The solution-generated [L-M3+] species further detected pyrophosphate ion (PPi) by exhibiting emission enhancement and a visible color change. The binding of Al3+/Ga3+ ions with chemosensor L4 was further supported by density functional theory studies. Reversibility for the detection of Al3+/Ga3+ ions was achieved by utilizing a suitable proton source. The multiionic response, reversibility, and optical visualization of the present chemosensors make them ideal for practical applications for real samples, which have been illustrated by paper-strip as well as polystyrene film-based detection.

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Section: Introductionmentioning

confidence: 99%

Turn-On Fluorescent Sensors for the Selective Detection of Al³⁺ (and Ga³⁺) and PPi Ions

Kumar

et al. 2019

Inorg. Chem.

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“…Moreover, the modification of the electronic layer at the GNP surface by the use of different ligands, a larger surface or a change of the medium's dielectric constant, leads to the modulation of the GNP plasmon band. This plasmon band allows the use of GNP for labeling, imaging, optical and electrochemical recognition, and diagnosis and therapy . Furthermore, most of cytotoxicity studies report low or no toxicity due to the inert nature of gold and the biocompatibility of the chosen ligands .…”

Section: Introductionmentioning

confidence: 99%

Gold nanoparticles in ophthalmology

Masse

Ouellette

Lamoureux

et al. 2018

Medicinal Research Reviews

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Many research projects are underway to improve the diagnosis and therapy in ophthalmology. Indeed, visual acuity deficits affect 285 million people worldwide and different strategies are being developed to strengthen patient care. One of these strategies is the use of gold nanoparticles (GNP) for their multiple properties and their ability to be used as both diagnosis and therapy tools. This review exhaustively details research developing GNPs for use in ophthalmology. The toxicity of GNPs and their distribution in the eye are described through in vitro and in vivo studies. All publications addressing the pharmacokinetics of GNPs administered in the eye are extensively reviewed. In addition, their use as biosensors or for imaging with optical coherence tomography is illustrated. The future of GNPs for ophthalmic therapy is also discussed. GNPs can be used to deliver genes or drugs through different administration routes. Their antiangiogenic and anti-inflammatory properties are of great interest for different ocular pathologies. Finally, GNPs can be used to improve stereotactic radiosurgery, brachytherapy, and photothermal therapy because of their many properties.

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“…Over the past two decades, fluorescent chemosensors have emerged as important alternatives to traditional qualitative and quantitative analysis technologies. Such sensors have been designed and synthesized for various uses, including biological, environmental, medical, and electromagnetic applications …”

Section: Methodsmentioning

confidence: 99%

A Novel Anthracene–Imidazole‐based Fluorescent “Turn‐on” Chemosensor for Fe³⁺

Shin

et al. 2018

Bulletin Korean Chem Soc

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Over the past two decades, fluorescent chemosensors have emerged as important alternatives to traditional qualitative and quantitative analysis technologies. Such sensors have been designed and synthesized for various uses, including biological, environmental, medical, and electromagnetic applications. 1-12Fluorescent sensors are highly sensitive, easy to use, and have wide applicability. In addition, such sensors can be used for analyzing metal ions quickly and accurately via the formation of a complex between the fluorophore and the metal ion being detected. 13The fluorophore anthracene and its derivatives have been used widely for fluorescence sensing, including the detection of metal ions, simple inorganic anions, and small organic molecules as well as for pH measurements. [14][15][16][17] These materials also exhibit very interesting photophysical properties: both chelation-enhanced fluorescence (CHEF) and chelation-enhanced fluorescence quenching (CHEQ) have been observed during complex formation. [18][19][20][21][22] We had previously reported that 9, 10-bis(3-hydroxypropylamino-methyl)anthracene exhibits significant OFF-ON-type fluorescence responses after interacting with Fe 3+

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Applications of vitamin B6 cofactor pyridoxal 5′-phosphate and pyridoxal 5′-phosphate crowned gold nanoparticles for optical sensing of metal ions

Cited by 25 publications

References 40 publications

Turn-On Fluorescent Sensors for the Selective Detection of Al³⁺ (and Ga³⁺) and PPi Ions

Turn-On Fluorescent Sensors for the Selective Detection of Al³⁺ (and Ga³⁺) and PPi Ions

Gold nanoparticles in ophthalmology

A Novel Anthracene–Imidazole‐based Fluorescent “Turn‐on” Chemosensor for Fe³⁺

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Applications of vitamin B6 cofactor pyridoxal 5′-phosphate and pyridoxal 5′-phosphate crowned gold nanoparticles for optical sensing of metal ions

Cited by 25 publications

References 40 publications

Turn-On Fluorescent Sensors for the Selective Detection of Al3+ (and Ga3+) and PPi Ions

Turn-On Fluorescent Sensors for the Selective Detection of Al3+ (and Ga3+) and PPi Ions

Gold nanoparticles in ophthalmology

A Novel Anthracene–Imidazole‐based Fluorescent “Turn‐on” Chemosensor for Fe3+

Contact Info

Product

Resources

About

Turn-On Fluorescent Sensors for the Selective Detection of Al³⁺ (and Ga³⁺) and PPi Ions

Turn-On Fluorescent Sensors for the Selective Detection of Al³⁺ (and Ga³⁺) and PPi Ions

A Novel Anthracene–Imidazole‐based Fluorescent “Turn‐on” Chemosensor for Fe³⁺