Applied Swarm-based medicine: collecting decision trees for patterns of algorithms analysis

Panje, Cédric; Glatzer, Markus; Rappard, Joscha von; Rothermundt, Christian; Hundsberger, Thomas; Zumstein, Valentin; Plaßwilm, Ludwig; Putora, Paul Martin

doi:10.1186/s12874-017-0400-y

Cited by 35 publications

(38 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The recommendations on stage III N2 NSCLC within the guidelines were reduced to recommendations towards a definitive surgical approach (with neoadjuvant or adjuvant Ch/CRT), a definitive CRT approach or no preference (no specific recommendation for either RT or surgery and both being options). Decision criteria implemented were analysed and standardised if their meaning was not changed, as described by PANJE et al [25][26][27]. Universal criteria such as the ability to give informed consent were not included in this analysis.…”

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

International guidelines on stage III N2 nonsmall cell lung cancer: surgery or radiotherapy?

et al. 2020

Self Cite

View full text Add to dashboard Cite

Stage III N2 nonsmall cell lung cancer (NSCLC) is a complex disease with poor treatment outcomes. For patients in whom the disease is considered technically resectable, the main treatment options include surgery (with neoadjuvant or adjuvant chemotherapy/neoadjuvant chemoradiotherapy (CRT)) or CRT followed by adjuvant immunotherapy (dependent on programmed death ligand 1 status). As there is no clear evidence demonstrating a survival benefit between these options, patient preference plays an important role. A lack of a consensus definition of resectability of N2 disease adds to the complexity of the decision-making process. We compared 10 international guidelines on the treatment of NSCLC to investigate the recommendations on preoperatively diagnosed stage III N2 NSCLC. This comparison simplified the treatment paths to multimodal therapy based on surgery or radiotherapy (RT). We analysed factors relevant to decision-making within these guidelines. Overall, for nonbulky mediastinal lymph node involvement there was no clear preference between surgery and CRT. With increasing extent of mediastinal nodal disease, a tendency towards multimodal treatment based on RT was identified. In multiple scenarios, surgery or RT-based treatments are feasible and patient involvement in decision-making is critical.

show abstract

Section: Methodsmentioning

confidence: 99%

“…The resulting decision trees were analysed for consensus and dissent with the objective consensus methodology [25,29,30].…”

Section: Methodsmentioning

confidence: 99%

International guidelines on stage III N2 nonsmall cell lung cancer: surgery or radiotherapy?

et al. 2020

Self Cite

View full text Add to dashboard Cite

show abstract

“…Additionally, for ongoing studies, the respective coordinators were asked to check their data for insular criteria arising from the input of the different institutions. All projects were based on open questions to the participants with no specific decision criteria suggested to the experts [9]. During data collection and analysis, the decision criteria were homogenised to enable comparability within the individual projects (e.g.…”

Section: Methodsmentioning

confidence: 99%

Insular Decision Criteria in Clinical Practice: Analysis of Decision-Making in Oncology

et al. 2020

Self Cite

View full text Add to dashboard Cite

Background: Medical decision-making is complex and involves a variety of decision criteria, many of which are universally recognised. However, decision-making analyses have demonstrated that certain decision criteria are not used uniformly among clinicians. Aim: We describe decision criteria, which for various contexts are only used by a minority of decision makers. For these, we introduce and define the term "insular criteria". Methods: 19 studies analysing clinical decision-making based on decision trees were included in our study. All studies were screened for decisionmaking criteria that were mentioned by less than three local decision makers in studies involving 8-26 participants. Results: 14 out of the 19 included studies reported insular criteria. We identified 42 individual insular criteria. They could be intuitively allocated to seven major groups, these were: comorbidities, treatment, patients' characteristics/preferences, caretaker, scores, laboratory and tumour properties/ staging. Conclusion: Insular criteria are commonly used in clinical decision-making, yet, the individual decision makers may not be aware of them. With this analysis, we demonstrate the existence of insular criteria and their variety. In daily practice and clinical studies, awareness of insular criteria is important.

show abstract

“…The participants were initially asked to answer the following open question: “What is your treatment policy regarding pre‐ and/or postoperative chemotherapy in localized extremity STS?” For the purposes of the present analysis, additional treatment such as isolated limb perfusion (ILP) and regional hyperthermia (RH) were not considered, even though they supplement surgery, radiotherapy, and chemotherapy in some of the centers. The initial answers provided were collected and converted into decision trees by the coordinating center (St. Gallen), based on the objective consensus methodology as published previously . This process consisted of an initial manual transformation of the replies into simple decision trees; once these were created, the respondents were contacted again to fill in possible empty branches of the decision trees.…”

Section: Methodsmentioning

confidence: 99%

Pre- and Postoperative Chemotherapy in Localized Extremity Soft Tissue Sarcoma: A European Organization for Research and Treatment of Cancer Expert Survey

et al. 2017

Self Cite

View full text Add to dashboard Cite

The management of localized extremity soft tissue sarcomas (STS) is challenging and the role of pre- and postoperative chemotherapy is unclear and debated among experts. This study analyzed the decision-making process among 12 European experts on systemic therapy for STS. A wide range of recommendations among experts regarding the use of perioperative chemotherapy was discovered. Discrepancies in the use of decision criteria were also uncovered, including the definition of what constitutes high-risk cancer, which is a basis for many to recommend chemotherapy. Before any standardization is possible, a common use of decision criteria is necessary.

show abstract

Applied Swarm-based medicine: collecting decision trees for patterns of algorithms analysis

Cited by 35 publications

References 23 publications

International guidelines on stage III N2 nonsmall cell lung cancer: surgery or radiotherapy?

International guidelines on stage III N2 nonsmall cell lung cancer: surgery or radiotherapy?

Insular Decision Criteria in Clinical Practice: Analysis of Decision-Making in Oncology

Pre- and Postoperative Chemotherapy in Localized Extremity Soft Tissue Sarcoma: A European Organization for Research and Treatment of Cancer Expert Survey

Contact Info

Product

Resources

About