Background: Queuing Management System usage become a symbol of the efficiency of majority of hospital worldwide. Managing the length of the client waiting line effect on quality of care and patient satisfaction. Aim of the study: assess the effect of queue management system on quality of nursing care and patient satisfaction. Research Design: A quasi-experimental design was utilized. Setting: outpatient department at Saudi German Hospital Cairo. Subjects: A 40 nurses who working in outpatient clinics and a 42 patients. Tools for data collection; Five tools were used as follow; Queue Management System knowledge questionnaire, Observational checklist regarding Queue Management System practices, nurses' attitude toward Queue Management System questionnaire, Quality of nursing care questionnaire and patient satisfaction questionnaire Results: the study results showed that, there was highly statistical significant difference improvement of nurses' knowledge scores at post and follow up program phases compared with preprogram phase, also, the most of nurses had satisfactory practice level at post program and follow up phases compared with preprogram phase, in addition, there was highly statistical significant difference improvement of nurses' attitude scores regarding queue management system throughout post and follow up program phases ; and the most of patients reported that there was high quality of nursing care level during post program and follow up phases compared with preprogram phase, finally, there was highly statistical significant difference improvement of patient satisfaction scores throughout post and follow up program phases compared with preprogram phase. Conclusion: Applying Queuing Management System can increase patient satisfaction and Quality of care. Recommendations: Hospital management should apply Queuing Management System for any service with waiting lines, For Nurses they should attended the continuous education programs, while for patients they should give feedback regarding the system and quality of nursing care.