This chapter describes the various approaches to analyse, quantify and evaluate uncertainty along the phases of the product life cycle. It is based on the previous chapters that introduce a consistent classification of uncertainty and a holistic approach to master the uncertainty of technical systems in mechanical engineering. Here, the following topics are presented: the identification of uncertainty by modelling technical processes, the detection and handling of data-induced conflicts, the analysis, quantification and evaluation of model uncertainty as well as the representation and visualisation of uncertainty. The different approaches are discussed and demonstrated on exemplary technical systems.