Approach to histopathological incidental lesions after reduction mammoplasty

Derebaşınlıoğlu, Handan; Yilmaz, Sarper

doi:10.1007/s00238-019-01576-0

Cited by 2 publications

(3 citation statements)

References 18 publications

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“…The cancer rate in patients with no history of breast cancer in previous studies ranged from 0 to 1% 12–26 . Similar to those studies, the cancer rate in our study was 0.36%.…”

Section: Discussionsupporting

confidence: 89%

“…In our study, the rate of AMBL in patients with no history of breast cancer was 3.3%. The previous studies that included only patients with no history of breast cancer reported the rate of AMBL to be between 1.5 and 14% 5,7–26 . The wide range of reported rates of AMBL in different studies can be attributed to different pathological assessment methods of RM specimens between institutions.…”

Section: Discussionmentioning

confidence: 98%

“…In this context, previous studies that analysed RM specimens showed a higher rate of incidental breast cancer in patients with a history of breast cancer compared to patients with no history of breast cancer 5–11 . The rate of incidental atypical and malignant breast lesions (AMBL) in patients with no history of breast cancer ranged from 1.5 to 14% 5,7–26 . One of the most common findings in all these studies was the older age of patients with AMBL compared to patients with no AMBL.…”

Section: Introductionmentioning

confidence: 89%

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The rate of incidental atypical and malignant breast lesions in reduction mammoplasty specimens

et al. 2020

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Aims: Reduction mammoplasty (RM) is one of the most common plastic surgeries in the United States. We aimed to demonstrate the rate of incidental atypical and malignant breast lesions (AMBL) found in RM specimens and the impact of the number of submitted tissue sections on the rate of AMBL. Methods and results: We analysed our database for patients who had undergone reduction mammoplasty between 2000 and 2018. Patients with a history of breast cancer were excluded from the study. All pathology reports were analysed for AMBL (ALH, LCIS, FEA, ADH, DCIS, invasive carcinoma). The grossing protocol was to submit 10 sections from each breast between 2000 and 2013 and six sections between 2014 and 2018. One hundred and sixtynine of 5208 patients (3.3%) and 216 of 10 340 RM specimens (2.1%) showed at least one AMBL. Nineteen (0.36%) patients had incidental cancer. The median age of patients with AMBL was significantly higher than patients without ABL (aged 59 years versus 45 years). There was no cancer in patients aged <30 years. The age-controlled rate of overall AMBL as well as atypia and cancer only did not decrease by submitting fewer sections during the 2014-18 period compared to the 2010-13 period. Conclusions: Decreasing the number of tissue sections from 10 to six did not lead to a significant decrease in the rate of overall AMBL or cancer. Our data suggest that submitting six tissue sections from each breast for patients aged >30 years and two sections from each breast for patients aged <30 years would be sufficient.

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“…The cancer rate in patients with no history of breast cancer in previous studies ranged from 0 to 1% 12–26 . Similar to those studies, the cancer rate in our study was 0.36%.…”

Section: Discussionsupporting

confidence: 89%

Section: Discussionmentioning

confidence: 98%