Approach to Reconstruction of Cheek Defects

Başağaoğlu, Berkay; Bhadkamkar, Mohin A.; Hollier, Pierce C.; Reece, Edward M.

doi:10.1055/s-0038-1642640

Cited by 16 publications

(19 citation statements)

References 25 publications

(32 reference statements)

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“…5,6,7,8 Healing via secondary intention remains the simplest form of reconstruction and is useful for superficial defects less than 2 cm in diameter. 9 This method may also be used in combination with a purse-string suture to reduce the surface area of larger round/oval defects. However in using this technique, care must be taken to prevent distortion of surrounding tissues.…”

Section: Discussionmentioning

confidence: 99%

Use of a Cervicofacial Flap in Closing Large Defects Following Wide Local Excision of Complicated Preauricular Lesions

Akakpo

Luck

Chun

2020

Ann Otol Rhinol Laryngol

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Purpose: To describe innovative surgical technique for closure of large defect following complicated preauricular cyst excision secondary to prior failed excision attempts, infections, and drainage procedures. Preauricular cysts must be widely excised including any fistulous tracts in order to reduce recurrence rates; however, the resultant large local excision poses cosmetic challenges. Methods: Retrospective chart review of 3 patient cases who underwent excision of recurrent preauricular lesions involving cervical parotid flap closure. All three cases demonstrate complicated preauricular congenital cysts which were infected and had prior drainage, excision attempts, or sclerotherapy. A cervicoparotid flap was used to close all defects cosmetically with no facial nerve weakness and without distortion to the oral commissure or lateral canthus. Results/conclusions: There is a high recurrence rate seen with wide local congenital cyst excisions that have been previously excised, infected, and drained; as well as, cosmetically unfavorable outcomes utilizing traditional repair. Utilizing our closure technique which involves reconstructive local regional flap with cervicoparotid approach our 3 patients have had no reoccurance of cyst or infection. Our approach also maximizes cosmetic outcomes, with reduced scar visibility. Pre and postoperative photos will be shown.

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Section: Discussionmentioning

confidence: 99%

Use of a Cervicofacial Flap in Closing Large Defects Following Wide Local Excision of Complicated Preauricular Lesions

Akakpo

Luck

Chun

2020

Ann Otol Rhinol Laryngol

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“…Very large defects of the cheek or those that involve the deeper structures and create contour problems may require free tissue transfer (Başağaoğlu et al 2018). Fasciocutaneous flaps provide the best options in these circumstances because the tissue is relatively thin and does not undergo atrophy (Fig.…”

Section: Cheekmentioning

confidence: 99%

Reconstructive Options Following Surgery of Primary Melanoma

Moncrieff¹,

Gastman²,

Neves³

et al. 2019

Cutaneous Melanoma

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Choosing the optimal technique for wound management requires an understanding of the basic concepts and principles of wound healing, including skin tension, skin vascularity, and tissue compliance, together with a detailed knowledge of the local and regional anatomy. This chapter provides the reader with a framework outlining the various principles and concepts of wound closure to facilitate the management of defects after melanoma excision.

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“…Large full-thickness skin defects [ 1 , 2 ] remain a significant challenge in clinical care. At present, autologous or allogeneic skin grafting is still the main choice for clinicians.…”

Section: Introductionmentioning

confidence: 99%

The Stimulation of Macrophages by Systematical Administration of GM-CSF Can Accelerate Adult Wound Healing Process

Zhang

Jia

Zheng

et al. 2022

IJMS

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Skin wound repair remains a major challenge in clinical care, and various strategies have been employed to improve the repair process. Recently, it has been reported that macrophages are important for the regeneration of various tissues and organs. However, their influence on wound repair is unclear. Here, we aimed to explore whether macrophages would participate in the wound healing process and to explore new possibilities of treatment for skin defects. We firstly created a mouse full-thickness skin defect model to observe the distribution of macrophages in the regenerating tissue and then detected the influence of macrophages on skin defect repair in both macrophage-depletion and macrophage-mobilization models. We found that the number of macrophages increased significantly after skin defect and persisted during the process of wound repair. The regeneration process was significantly prolonged in macrophage-depleted animals. RT-qPCR and ELISA assays further demonstrated that the expression of growth factors was perturbed in the regenerating tissue. The activation of macrophages by granulocyte-macrophage colony-stimulating factor (GM-CSF) injection could significantly improve wound healing, accompanied with an upregulation of the expression of various growth factors. In conclusion, the current study demonstrated that macrophages are critical for skin regeneration and that GM-CSF exhibited therapeutic potential for wound healing.

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Approach to Reconstruction of Cheek Defects

Cited by 16 publications

References 25 publications

Use of a Cervicofacial Flap in Closing Large Defects Following Wide Local Excision of Complicated Preauricular Lesions

Use of a Cervicofacial Flap in Closing Large Defects Following Wide Local Excision of Complicated Preauricular Lesions

Reconstructive Options Following Surgery of Primary Melanoma

The Stimulation of Macrophages by Systematical Administration of GM-CSF Can Accelerate Adult Wound Healing Process

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