2023
DOI: 10.1007/s10709-023-00196-8
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Approaches to increase the validity of gene family identification using manual homology search tools

Benjamin J. Nestor,
Philipp E. Bayer,
Cassandria G. Tay Fernandez
et al.

Abstract: Identifying homologs is an important process in the analysis of genetic patterns underlying traits and evolutionary relationships among species. Analysis of gene families is often used to form and support hypotheses on genetic patterns such as gene presence, absence, or functional divergence which underlie traits examined in functional studies. These analyses often require precise identification of all members in a targeted gene family. Manual pipelines where homology search and orthology assignment tools are … Show more

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