2022
DOI: 10.3390/ijerph19169801
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Approaches to Peripheral Artery Disease in Diabetes: Are There Any Differences?

Abstract: Peripheral artery disease (PAD) increases the risk of diabetes, while diabetes increases the risk of PAD, and certain symptoms in each disease increase the risk of contracting the other. This review aims to shed light on this harmful interplay between the two disorders, with an emphasis on the phenotype of a patient with both diabetes and PAD, and whether treatment should be individualized in this high-risk population. In addition, current guideline recommendations for the treatment of PAD were analyzed, in an… Show more

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Cited by 34 publications
(28 citation statements)
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“…Although diabetes is a frequent comorbidity in patients with CVD, the exact correlation between the two is not yet known [ 43 ]. Similarly, unlike in the arterial system, where the presence of diabetes may accelerate the incidence of in-stent restenosis (ISR) [ 44 , 45 ], the effect of diabetes on ISR in venous stents is not clearly known.…”
Section: Resultsmentioning
confidence: 99%
“…Although diabetes is a frequent comorbidity in patients with CVD, the exact correlation between the two is not yet known [ 43 ]. Similarly, unlike in the arterial system, where the presence of diabetes may accelerate the incidence of in-stent restenosis (ISR) [ 44 , 45 ], the effect of diabetes on ISR in venous stents is not clearly known.…”
Section: Resultsmentioning
confidence: 99%
“…In this case, acne represented the only possible entry that could be detected [27]. "Hidden" entry portals for IE could be discrete skin lesions in patients with diabetes mellitus and peripheral artery disease [28] or micro-organisms of gastrointestinal origin (gastrointestinal polyps, tumors, etc.) [29].…”
Section: Current Reports and Actual Evidencementioning
confidence: 98%
“…Untreated or advanced stage PAD may lead to tissue loss and amputation [ 13 , 14 ]. Risk factors for PAD include age, race, smoking, hypertension, diabetes, and hyperlipidemia [ 15 , 16 , 17 ]. PAD is associated with considerable physical and psychosocial disease burden, primarily resulting from impaired functional status and quality of life [ 18 , 19 , 20 , 21 , 22 ] Studies conducted in the U.S. and Hungary have highlighted that functional impairment and pain resulting from lower extremity arterial ischemia leads to reduced quality of life and, consequently, a considerable proportion of PAD patients experience severe symptoms of anxiety and depression.…”
Section: Introductionmentioning
confidence: 99%