2024
DOI: 10.1007/s40135-024-00326-1
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Approaches to Restoring Lacrimal Gland Function: From stem Cells to Tissue Engineering

Alexander C. Lieu,
Marissa K. Shoji,
Vinay K. Aakalu
et al.

Abstract: Purpose of Review We review the latest developments in restoration of lacrimal gland function in dry eye disease and promising methods to generate functional lacrimal gland units. Recent Findings Mesenchymal stem cell delivery demonstrated improved tear secretion in dry eye mouse models and early human studies, likely through immune modulation and lacrimal gland repair mechanisms. Advances in regenerative strategies to create functional lacrimal gland unit… Show more

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