Approaches to the assessment of awareness: Conceptual issues

Marková, Ivana; Berríos, Germán E.

doi:10.1080/09602010500373396

Cited by 29 publications

(19 citation statements)

References 70 publications

(108 reference statements)

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“…Clare, 2004a;2004b;Markova and Berrios, 2006;Roberts et al, 2009). It is beyond the scope of this paper to offer a comprehensive discussion of the issue but detailed reviews are available elsewhere (e.g.…”

Section: Discussionmentioning

confidence: 99%

Awareness of olfactory deficits in healthy aging, amnestic mild cognitive impairment and Alzheimer's disease

Bahar‐Fuchs

Moss

Rowe

et al. 2011

Int. Psychogeriatr.

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Treating awareness of olfactory function as a unitary construct can be misleading, and there is a poor relationship between subjective and objective measures of olfactory ability. Our preliminary data suggest that unawareness of olfactory decline does not improve the identification of patients with MCI who are more likely to be in the prodromal phase of AD. Replication in a larger cohort is needed to support these findings.

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Section: Discussionmentioning

confidence: 99%

Awareness of olfactory deficits in healthy aging, amnestic mild cognitive impairment and Alzheimer's disease

Bahar‐Fuchs

Moss

Rowe

et al. 2011

Int. Psychogeriatr.

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“…At later stages of HD, one would expect to observe unawareness of various symptoms. If this hypothesis were verified, this would argue against the view that awareness of deficits should be examined as a general process in HD [5], [36], and would instead suggest a sequential impairment of distinct processes of awareness of specific deficits parallel to disease evolution [37], [38]. Future studies should assess intra-subject comparisons of awareness of different symptoms (such as motor or behavioral symptoms), with objective and subjective measures in order to understand the time course of the appearance of the lack of awareness in each domain and to delineate the usefulness of this kind of questionnaire at each stage and for each domain.…”

Section: Discussionmentioning

confidence: 99%

Awareness of Memory Deficits in Early Stage Huntington's Disease

et al. 2013

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Patients with Huntington's disease (HD) are often described as unaware of their motor symptoms, their behavioral disorders or their cognitive deficits, including memory. Nevertheless, because patients with Parkinson's disease (PD) remain aware of their memory deficits despite striatal dysfunction, we hypothesize that early stage HD patients in whom degeneration predominates in the striatum can accurately judge their own memory disorders whereas more advanced patients cannot. In order to test our hypothesis, we compared subjective questionnaires of memory deficits (in HD patients and in their proxies) and objective measures of memory dysfunction in patients. Forty-six patients with manifest HD attending the out-patient department of the French National Reference Center for HD and thirty-three proxies were enrolled. We found that HD patients at an early stage of the disease (Stage 1) were more accurate than their proxies at evaluating their own memory deficits, independently from their depression level. The proxies were more influenced by patients' functional decline rather than by patients' memory deficits. Patients with moderate disease (Stage 2) misestimated their memory deficits compared to their proxies, whose judgment was nonetheless influenced by the severity of both functional decline and depression. Contrasting subjective memory ratings from the patients and their objective memory performance, we demonstrate that although HD patients are often reported to be unaware of their neurological, cognitive and behavioral symptoms, it is not the case for memory deficits at an early stage. Loss of awareness of memory deficits in HD is associated with the severity of the disease in terms of CAG repeats, functional decline, motor dysfunction and cognitive impairment, including memory deficits and executive dysfunction.

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“…More recently, a third method (the composite method) has been used to measure awareness deficits using a combination of discrepancy methods and clinicians' assessments of patient's responses to interview questions [23]. This composite method is believed to provide a more global and comprehensive picture of a patient's perception of their abilities.…”

Section: Introductionmentioning

confidence: 99%

“…Currently there are two main methods of assessing awareness deficits in the TBI population; discrepancy methods and clinicians' assessments of awareness deficits [23].…”

Section: Introductionmentioning

confidence: 99%