In this paper, we establish the Hitchin-Kobayashi correspondence for the I±-holomorphic quiver bundle E = (E, φ) over a compact generalized Kähler manifold (X, I+, I−, g, b) such that g is Gauduchon with respect to both I+ and I−, namely E is (α, σ, τ )-polystable if and only if E admits an (α, σ, τ )-Hermitian-Einstein metric.where ·, · denotes the natural inner product on T X ⊕ T * X. Definition 2.2. ([12]) A manifold X is called a generalized Kähler manifold if it carries the data (I + , I − , g, b), where• I ± are two complex structures on X,• g is a Riemannian metric on X, • b is a two-form on X, • I ± are parallel with respect to the connections ∇ ± = ∇ ± 1 2 g −1 H, respectively, where ∇ is the Levi-Civita connection of g and H = db.The generalized Calabi-Yau manifold is an important kind of generalized Kähler manifold.Definition 2.3. ([13])A generalized Calabi-Yau manifold is a generalized Kähler manifold (X, J 1 , J 2 ) such that both nowhere vanishing pure spinors ψ 1 , ψ 2 corresponding to J 1 , J 2 , respectively satisfy the following conditions