Let T be a tree space (or tree network) represented by a weighted tree with t vertices, and S be a set of n stochastic points in T , each of which has a fixed location with an independent existence probability. We investigate two fundamental problems under such a stochastic setting, the closest-pair problem and the nearest-neighbor search. For the former, we study the computation of the -threshold probability and the expectation of the closest-pair distance of a realization of S. We propose the first algorithm to compute the -threshold probability in O(t + n log n + min{tn, n 2 }) time for any given threshold , which immediately results in an O(t + min{tn 3 , n 4 })-time algorithm for computing the expected closest-pair distance. Based on this, we further show that one can compute a (1 + ε)-approximation for the expected closest-pair distance in O(t + ε −1 min{tn 2 , n 3 }) time, by arguing that the expected closest-pair distance can be approximated via O(ε −1 n) threshold probability queries. For the latter, we study the k mostlikely nearest-neighbor search (k-LNN) via a notion called k most-likely Voronoi Diagram (k-LVD). We show that the size of the k-LVD Ψ S T of S on T is bounded by O(kn) if the existence probabilities of the points in S are constant-far from 0. Furthermore, we establish an O(kn) average-case upper bound for the size of Ψ S T , by regarding the existence probabilities as i.i.d. random variables drawn from some fixed distribution. Our results imply the existence of an LVD data structure which answers k-LNN queries in O(log n + k) time using average-case O(t + k 2 n) space, and worst-case O(t + kn 2 ) space if the existence probabilities are constant-far from 0. Finally, we also give an O(t + n 2 log n + n 2 k)-time algorithm to construct the LVD data structure.