APSIC guide for prevention of Central Line Associated Bloodstream Infections (CLABSI)

Abstract

This document is an executive summary of the APSIC Guide for Prevention of Central Line Associated Bloodstream Infections (CLABSI). It describes key evidence-based care components of the Central Line Insertion and Maintenance Bundles and its implementation using the quality improvement methodology, namely the Plan-Do-Study-Act (PDSA) methodology involving multidisciplinary process and stakeholders. Monitoring of improvement over time with timely feedback to stakeholders is a key component to ensure the success of implementing best practices. A surveillance program is recommended to monitor outcomes and adherence to evidence-based central line insertion and maintenance practices (compliance rate) and identify quality improvement opportunities and strategically targeting interventions for the reduction of CLABSI.

Advances in Medical Nutrition Therapy: Parenteral Nutrition

“…Global guidelines for the prevention of intravascular catheter-related infections [36][37][38][39] emphasize the importance of educational programs for healthcare workers and patients regarding infection protection and hand decontamination. A recently published RCT by Inchingolo et al showed that educational programs with or without port protectors substantially reduced the rate of both central line-associated bloodstream infections and central venous colonization [40].…”

“…Results from the 3SITE study showed that the risk for catheter-related bloodstream infections or symptomatic vein thromboses in femoral sites was 3.1 times higher than in subclavian sites, and 2.1 times higher in jugular vein sites than in subclavian sites [41]. It was further recommended that an ultrasound be used to reduce the number of insertions attempts and, therefore, the chance of infection [37][38][39]. Other efforts are being investigated to further reduce infection complications, such as chlorhexidine-impregnated dressings [42][43][44], which is now also a part of recent global guidelines [37][38][39].…”

“…It was further recommended that an ultrasound be used to reduce the number of insertions attempts and, therefore, the chance of infection [37][38][39]. Other efforts are being investigated to further reduce infection complications, such as chlorhexidine-impregnated dressings [42][43][44], which is now also a part of recent global guidelines [37][38][39]. In an RCT by Wouters et al comparing taurolidine locks to 0.9% saline locks, a significant reduction in catheter-related bloodstream Global guidelines for the prevention of intravascular catheter-related infections [36][37][38][39] emphasize the importance of educational programs for healthcare workers and patients regarding infection protection and hand decontamination.…”

Uso de kits desechables para optimizar tiempos, movimientos y apego a protocolos de la terapia intravenosa

“…Un ejemplo de esto es la higiene de manos 11 , uso de apósito estéril transparente 12 , programas de educación establecidos en correcta instalación y mantenimiento de acceso vasculares [13][14] , uso de clorhexidina como antiséptico para la preparación de la piel [15][16][17] , uso de la barrera máxima durante la inserción y mantenimiento [18][19][20][21][22][23][24][25] , así como uso de listas de verificación (check-list) de procedimientos 26 .…”

Infection Prevention and Control in Asia: Current Evidence and Future Milestones

“…In addition, several viral pandemics and annual influenza strains have originated in the Asia-Pacific region, which, together, has global implications for population health.The prevention, control, and reporting of MDROs and healthcare-associated infections (HAIs) benefit from effective data dissemination plans and harmonized surveillance systems. HAIs compromise patient safety because they are preventable and serve as a reservoir for MDROs, which are associated with excess length of hospital stay, increased antimicrobial drug exposure, and excess costs [1][2][3][4][5]. In the Asia-Pacific region, the risks of HAIs have been estimated to be 2-20 times higher than in developed countries, with up to 25% of hospitalized patients reported to have acquired infections [4].…”