Aptamer-functionalized magnetic graphene oxide nanocarrier for targeted drug delivery of paclitaxel

Hussien, Nizamudin Awel; Işıklan, Nuran; Türk, Mustafa

doi:10.1016/j.matchemphys.2018.03.015

Cited by 76 publications

(14 citation statements)

References 56 publications

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“…Cancer is one of the most malignant diseases in the world and is a leading cause of human death [1,2]. Although chemotherapy is commonly used in the clinic cancer treatment, several key issues including low therapeutic efficiency and extensive side effects seriously limit its application [3].…”

Section: Introductionmentioning

confidence: 99%

Facile Approach to Prepare rGO@Fe3O4 Microspheres for the Magnetically Targeted and NIR-responsive Chemo-photothermal Combination Therapy

et al. 2020

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Near-infrared (NIR)-light responsive graphene have been shown exciting effect on cancer photothermal ablation therapy. Herein, we report on the preparation of Fe 3 O 4-decorated hollow graphene microspheres (rGO@Fe 3 O 4) by a facile spray drying and coprecipitation method for the magnetically targeted and NIR-responsive chemophotothermal combination therapy. The microspheres displayed very high specific surface area (~120.7 m 2 g −1) and large pore volume (~1.012 cm 3 g −1), demonstrating distinct advantages for a high loading capacity of DOX (1 8.43%). NIR triggered photothermal effect of the rGO@Fe 3 O 4 microspheres responded in an on-off manner and induced a high photothermal conversion efficiency. Moreover, The Fe 3 O 4 on the microspheres exhibited an excellent tumor cells targeting ability. The chemo-photothermal treatment based on rGO@Fe 3 O 4 /DOX showed superior cytotoxicity towards Hela cells in vitro. Our studies indicated that rGO@Fe 3 O 4 /DOX microcapsules have great potential in combined chemo-photothermal cancer treatment.

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Section: Introductionmentioning

confidence: 99%

Facile Approach to Prepare rGO@Fe3O4 Microspheres for the Magnetically Targeted and NIR-responsive Chemo-photothermal Combination Therapy

et al. 2020

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“…Magnetic graphene oxide (MGO) based on graphene is a 2D carbon nanostructure with one‐atom thickness that contains hydroxyl, epoxide, carboxyl, and carbonyl functional groups , and has been considered to be a promising adsorbent for environmental remediation systems . Moreover, the magnetization of MGO has the advantage of easy solid‐liquid separation using an external magnetic field, showing high adsorption capability and recovery towards pollutants.…”

Section: Introductionmentioning

confidence: 99%

Deep eutectic solvents skeleton typed molecularly imprinted chitosan microsphere coated magnetic graphene oxide for solid‐phase microextraction of chlorophenols from environmental water

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2020

J of Separation Science

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Novel molecularly imprinted chitosan microspheres were prepared on the surface of magnetic graphene oxide, with deep eutectic solvents both as a functional monomer and template. The prepared molecularly imprinted chitosan microspheres‐magnetic graphene oxide was characterized by scanning electron microscopy, Fourier transform infrared spectroscopy, X‐ray diffraction, Brunauer‐Emmett‐Teller surface area, thermogravimetric analysis were subsequently combined with solid‐phase micro‐extraction for simultaneous separation and enrichment of the extraction of chlorophenols from environmental water. Factors affecting the extraction efficiency of chlorophenols were optimized using response surface methodology. The actual extraction capacities under the optimal conditions (liquid to solid ratio = 3, cycles of adsorption/desorption = 5, 40°C extraction temperature, and extraction time for 35 min) were 86.90 mg/g. Compared to the traditional materials, the molecularly imprinted chitosan microspheres‐magnetic graphene oxide produced higher selectivity and extraction capacity.

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“…Graphene sheets have high reinforcing properties due to their high specific surface area of about 2630 m 2 g −1 [26]. The good biological properties of graphene have led to its extensive study in biological applications such as bioimaging, drug delivery, and orthopedics [27][28][29][30].…”

Section: Introductionmentioning

confidence: 99%

Characterization of hydroxyapatite-reduced graphene oxide nanocomposites consolidated via high frequency induction heat sintering method

Nosrati

Sarraf-Mamoory

Kazemi

et al. 2020

Journal of Asian Ceramic Societies

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Aptamer-functionalized magnetic graphene oxide nanocarrier for targeted drug delivery of paclitaxel

Cited by 76 publications

References 56 publications

Facile Approach to Prepare rGO@Fe3O4 Microspheres for the Magnetically Targeted and NIR-responsive Chemo-photothermal Combination Therapy

Facile Approach to Prepare rGO@Fe3O4 Microspheres for the Magnetically Targeted and NIR-responsive Chemo-photothermal Combination Therapy

Deep eutectic solvents skeleton typed molecularly imprinted chitosan microsphere coated magnetic graphene oxide for solid‐phase microextraction of chlorophenols from environmental water

Characterization of hydroxyapatite-reduced graphene oxide nanocomposites consolidated via high frequency induction heat sintering method

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