2017
DOI: 10.13188/2328-1723.1000016
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Aptamer Utility in Sensor Platformsfor the Detection of Toxins and Heavy Metals

Abstract: Nucleic acid research has expanded in recent years through the development of an in vitro methodology for the derivation of functional nucleic acids, capable of binding to specific targets with high specificity and sensitivity. These activities are similar to those of antibodies, yet the single-stranded oligonucleotide, called aptamer, can be readily created on a large-scale using solid-phase oligonucleotide synthesis. This relative ease of synthesis has made aptamers a highly versatile tool for the detection … Show more

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