Aquatic Plants Exposed to Pharmaceuticals: Effects and Risks

Brain, Richard A.; Hanson, Mark L.; Solomon, Keith R.; Brooks, Bryan W.

doi:10.1007/978-0-387-71724-1_3

Cited by 128 publications

(87 citation statements)

References 140 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…EC x values are based on the nonlinear regression model with the greatest adjusted R oxytetracycline was 6,730 lg/L. Similar trends have been found in aquatic plants exposed to tetracyclines (Brain et al 2008a). Among the sulfonamides, sulfamethoxazole and sulfamethazine typically exhibited potency differences less than one order of magnitude within a plant species.…”

Section: Interclass and Intraclass Differencesmentioning

confidence: 53%

“…Although these studies show that uptake of some PPCPs in terrestrial plants is possible, there remains a general paucity of studies evaluating the potential for phytotoxic effects after exposure. A review of the literature on the effects of pharmaceuticals on aquatic macrophytes indicates the potential for phytotoxicity, particularly in the case of antibiotics that target evolutionarily conserved target sites, such as those in plastid organelles of bacterial origin common to both bacteria and plants (Brain et al 2008a). Other toxic mechanisms may be less obvious, such as the tetracycline class of antibiotics that induces toxicity in plants directly through the chelating of metal nutrients (Nickell and Gordon 1961).…”

mentioning

confidence: 99%

See 1 more Smart Citation

Effects of Ten Antibiotics on Seed Germination and Root Elongation in Three Plant Species

Hillis

Fletcher

Solomon

et al. 2010

Arch Environ Contam Toxicol

Self Cite

171

View full text Add to dashboard Cite

We applied a screening-level phytotoxicity assay to evaluate the effects of 10 antibiotics (at concentrations ranging from 1 to 10,000 lg/L) on germination and early plant growth using three plant species: lettuce (Lactuca sativa), alfalfa (Medicago sativa), and carrot (Daucus carota). The range of phytotoxicity of the antibiotics was large, with EC 25 s ranging from 3.9 lg/L to [10,000 lg/L. Chlortetracycline, levofloxacin, and sulfamethoxazole were the most phytotoxic antibiotics. D. carota was the most sensitive plant species, often by an order of magnitude or more, followed by L. sativa and then M. sativa. Plant germination was insensitive to the antibiotics, with no significant decreases up to the highest treatment concentration of 10,000 lg/L. Compared with shoot and total length measurements, root elongation was consistently the most sensitive end point. Overall, there were few instances where measured soil concentrations, if available in the publicly accessible literature, would be expected to exceed the effect concentrations of the antibiotics evaluated in this study. The use of screening assays as part of a tiered approach for evaluating environmental impacts of antibiotics can provide insight into relative species sensitivity and serve as a basis by which to screen the potential for toxic effects of novel compounds to plants.

show abstract

Section: Interclass and Intraclass Differencesmentioning

confidence: 53%

mentioning

confidence: 99%

Effects of Ten Antibiotics on Seed Germination and Root Elongation in Three Plant Species

Hillis

Fletcher

Solomon

et al. 2010

Arch Environ Contam Toxicol

Self Cite

171

View full text Add to dashboard Cite

show abstract

“…Toxicity of PPCPs to algae and other aquatic organisms has been extensively reviewed previously (Brain et al 2008;Brausch et al 2012;Fent et al 2006;Wilkinson et al 2016).…”

Section: Introductionmentioning

confidence: 99%

Removal of pharmaceuticals and personal care products from wastewater using algae-based technologies: a review

Wang

Liu

et al. 2017

Rev Environ Sci Biotechnol

150

View full text Add to dashboard Cite

Pharmaceuticals and personal care products (PPCPs) consist of a variety of compounds extensively used for the treatment of human and animal diseases and for health or cosmetic reasons. PPCPs are considered as emerging environmental contaminants due to their ubiquitous presence in the environment and high environmental risks. In wastewater treatment plants using conventional activated sludge processes, many PPCPs cannot be efficiently removed. Therefore, there is an increasing need for more effective and cost-efficiency ways of removing PPCPs while treating wastewater. Algae-based technologies have recently attracted growing attentions for their potential application in wastewater treatment and hazardous contaminant removal, which are advantages in reducing operation cost while generating valuable products and sequestrating greenhouse gases at the same time. This work reviews the up-to date researches to reveal potential toxic effects of PPCPs on algae and algae-bacteria consortia, identify mechanisms involved in PPCP removal, and assess the fate of PPCPs in algae-based treatment systems. Current researches suggest that algae and algae-bacteria consortia have great potentials in PPCP removal but more works are required before algae-based technologies can be implemented in large scales. Knowledge gaps are identified and further research focuses are proposed in this review.

show abstract

“…At high concentrations it has been suggested tetracycline toxicity on plants is induced directly through the chelating of metal nutrients (Nickell and Gordon, 1961;Brain et al, 2008). At the low concentrations tested in this experiment it is therefore not surprising that most of the tetracyclines were relatively innocuous to root-organ cultures and fungi.…”

Section: Possible Mechanisms Of Amf Toxicitymentioning

confidence: 60%

Structural responses of Daucus carota root-organ cultures and the arbuscular mycorrhizal fungus, Glomus intraradices, to 12 pharmaceuticals

et al. 2008

Self Cite

View full text Add to dashboard Cite

a b s t r a c tPharmaceuticals and personal care products may enter the terrestrial environment through the amendment of agricultural soils with manure or biosolids with potential impacts on beneficial soil microbe populations. The beneficial symbiotic relationship between most plant species and arbuscular mycorrhizal fungi is a primary determinant of plant health and soil fertility. As such, there is increasing recognition of the need to study the impacts of anthropogenic stressors on plant-microbe interactions in soil ecotoxicology studies and risk assessment. A case study exploring the use of root-organ cultures to evaluate the effects of 12 common veterinary and human-use pharmaceuticals on the arbuscular mycorrhizal fungus, Glomus intraradices grown on Daucus carota root-organ cultures is presented. The bioassays were conducted over a 28-day exposure period at concentrations up to 1000 lg l À1 . Root length and the fungal endpoints of hyphal growth and spore production were evaluated weekly during the study. Sulfamethoxazole and atorvastatin were the most phytotoxic compounds with EC 50 values of 45 lg l À1 and 65 lg l À1 , respectively. Three compounds exhibited selective mycotoxicity, whereby the fungal symbiont was adversely affected at concentrations significantly less than that calculated for root length. The EC 50 for G. intraradices hyphal length was 45 lg l À1 for doxycycline, while carbamazepine and 17-a-ethynyl estradiol targeted spore production with EC 50 values of 113 and 116 lg l À1 , respectively. The assay results indicate that the root lengths responded quickly to the presence of phytotoxic pharmaceuticals in the culture medium. Hyphal length is a sensitive endpoint after 21 days exposure, while spore production requires 28 days exposure before significant differences could be detected. Root-organ cultures provide an effective means to evaluate chemical stressors on arbuscular mycorrhizal fungi and can be used to screen for root-based phytotoxicity.

show abstract

Aquatic Plants Exposed to Pharmaceuticals: Effects and Risks

Cited by 128 publications

References 140 publications

Effects of Ten Antibiotics on Seed Germination and Root Elongation in Three Plant Species

Effects of Ten Antibiotics on Seed Germination and Root Elongation in Three Plant Species

Removal of pharmaceuticals and personal care products from wastewater using algae-based technologies: a review

Structural responses of Daucus carota root-organ cultures and the arbuscular mycorrhizal fungus, Glomus intraradices, to 12 pharmaceuticals

Contact Info

Product

Resources

About