Aquatic systems: maintaining, mixing and mobilising antimicrobial resistance?

Taylor, Nick; Verner–Jeffreys, David W.; Baker‐Austin, Craig

doi:10.1016/j.tree.2011.03.004

Cited by 283 publications

(204 citation statements)

References 62 publications

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“…For example, in Italy, ETM in aquatic environments has been selected as one of a restricted group of priority pollutants identified by three conserved standards, thus, it is worthwhile to pay attention to its levels in surface waters (Lee et al, 2008). Apart from chemical pollution caused by the antibiotics themselves, the use of antibiotics may also accelerate the development of antibiotic resistance genes (ARGs) and bacteria, which could lead to health risks to humans and animals (Kummerer, 2004;Taylor et al, 2011;Zhang et al, 2009). One of the major factors causing the collapse of the Taiwan shrimp farming industry in 1988 was the indiscriminate use of antibiotics, which resulted in resistant pathogens (Lin, 1989).…”

Section: Environmental Risk Assessment and Significance Of Resultsmentioning

confidence: 99%

“…These systems are evolving to become a significant contributor to meet the demands for seafood (Sapkota et al, 2008). Moreover, hygienic shortcomings in raising methods, including increased stocking densities, the crowding of farming sites in coastal waters, a lack of sanitary barriers and a failure to isolate aquaculture base units with infected animals (Cabello, 2006;Reboucas et al, 2011;Taylor et al, 2011), have increased the possibility of rapid spreading of infection. This possibility also results in an augmented use of prophylactic antibiotics, often with the misguided goal of compensating for these sanitary shortcomings (Cabello, 2006).…”

Section: Introductionmentioning

confidence: 99%

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Occurrence and distribution of antibiotics in the Beibu Gulf, China: Impacts of river discharge and aquaculture activities

Zheng

Zhang

Wang

et al. 2012

Marine Environmental Research

209

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Section: Environmental Risk Assessment and Significance Of Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Occurrence and distribution of antibiotics in the Beibu Gulf, China: Impacts of river discharge and aquaculture activities

Zheng

Zhang

Wang

et al. 2012

Marine Environmental Research

209

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“…Although the occurrence of VRE in Japan is much lower in comparison with that in these regions, expansion of VRE nosocomial infections is considered a public health concern [16]. With the emergence of VRE, these enterococci can be present in a same area, and it is possible that the bacteria including enterococci are capable of sharing antibiotic resistance genes among members of the microbial communities that exist in the natural environment, such as soil and water [17].…”

Section: Introductionmentioning

confidence: 99%

Antibiotic Resistance Profiling and Genotyping of Vancomycin-Resistant Enterococci Collected from an Urban River Basin in the Provincial City of Miyazaki, Japan

Nishiyama

Ogura

Hayashi

et al. 2017

Water

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Abstract:The distribution characteristics of vancomycin-resistant enterococci (VRE) and the resistance of enterococcus isolates to various antibiotics were investigated in Yae River, which flows through Miyazaki city, Japan. The prevalence of VRE among specimens collected from the urban river basin using mEI agar was 0.9% (2 of 226 enterococcal isolates). In the 333 enterococcal isolates obtained using mEI agar or vancomycin-supplemented mEI agar, the possession of the vancomycin-resistant genes (vanA, vanB, vanC1, and vanC2/C3) was examined using multiplex PCR analysis. Although VRE possessing vanA and vanB were not detected in any isolates, isolates possessing vanC2/C3 were detected at all sampling sites and on all days. All isolates (101 strains) possessing vanC2/C3 that were obtained on vancomycin-supplemented mEI agar were identified as E. casseliflavus and analyzed for genotypes using pulse-field gel electrophoresis (PFGE) analysis. These E. casseliflavus isolates revealed them to be genetically highly divergent strains, suggesting that many contamination sources were present in this study area. Many of the enterococcal isolates obtained were resistant to erythromycin, ciprofloxacin, and tetracycline; enterococci distributed in the studied urban river basin are resistant to universally applicable antibiotics. These results indicate that VRE carrying vanC2/C3 are distributed in Yae River, and the sources of VRE are scattered across the river basin.

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“…The environment may be as reservoirs of ARGs, which could be acquired by clinical pathogens through horizontal gene transfer (Forsberg et al, 2012;Yang et al, 2013). Aquatic system serves as a key milieu for the environmental release, mixing, persistence and spread of ARGs, and antibiotic resistance bacteria (Allen et al, 2010;Taylor et al, 2011). Evidences suggested that waste discharges from anthropogenic compartments, such as animal feedlots and wastewater treatment plants significantly contributed to the pollution of ARGs in downstream rivers (Pruden et al, 2012;Hsu et al, 2014).…”

Section: Introductionmentioning

confidence: 99%

Antibiotic resistance genes occurrence and bacterial community composition in the Liuxi River

Xiong

Sun

Ding

et al. 2014

Front. Environ. Sci.

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Antibiotic resistance genes (ARGs) in the environment have paid great concern due to their health risk. We investigated antibiotics concentrations (tetracyclines, sulfonamides, and fluoroquinolones), ARGs abundances (tetracycline, sulfonamide, and plasmid-mediated quinolone resistance (PMQR) genes), and bacterial community composition in sediment and water samples in the Liuxi River, China. Antibiotics concentrations were determined by ultra-performance liquid chromatography-electrospray tandem mass spectrometry. ARGs abundances were quantified by a culture-independent method. Bacterial community composition was analyzed by metagenomic approach based on Ion Torrent Personal Genome Machine platform. Antibiotics concentrations were at the levels of 1.19-622 ug kg −1 in sediment samples and below the limit of detection to 127 ng L −1 in water samples. Relative abundances (ARGs copies/16S rRNA gene copies) of detected ARGs were at the range of 10 −5 to 10 −2 . The dominant phyla were Proteobacteria, Bacteroidetes, and Verrucomicrobia in sediment samples, and were Proteobacteria, Actinobacteria, and Bacteroidetes in water samples. The results indicated that the river environment was contaminated by antibiotics and may be as a reservoir of ARGs. This study provided quantitative data on antibiotics, ARGs and bacterial community composition in the Liuxi River, a geographical location different from the reported studies.

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Aquatic systems: maintaining, mixing and mobilising antimicrobial resistance?

Cited by 283 publications

References 62 publications

Occurrence and distribution of antibiotics in the Beibu Gulf, China: Impacts of river discharge and aquaculture activities

Occurrence and distribution of antibiotics in the Beibu Gulf, China: Impacts of river discharge and aquaculture activities

Antibiotic Resistance Profiling and Genotyping of Vancomycin-Resistant Enterococci Collected from an Urban River Basin in the Provincial City of Miyazaki, Japan

Antibiotic resistance genes occurrence and bacterial community composition in the Liuxi River

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