Aqueous 2% chlorhexidine-induced chemical burns in an extremely premature infant: Figure 1

Abstract

Patient consent Obtained from the parentsProvenance and peer review Not commissioned; externally peer reviewed.

Safety of chlorhexidine gluconate used for skin antisepsis in the preterm infant

“…28 A recent case report also identified an infant born at 25 weeks gestation who sustained skin burns after exposure to a 2% aqueous CHG solution before umbilical catheter placement in the first few hours of life. 29 The most common reported event after CHG exposure is skin irritation. In most cases, whether this irritation is caused by true allergy, hypersensitivity reaction, occlusive dressings or the alcohol-based solution is unknown.…”

pH, Temperature, Hydration of the Stratum Corneum of the Dorsal Hand and the Cord Area, and Acid Mantle Formation during Early Days of life in High-risk Newborns

“…그러나 이들 연구의 대부분은 생후 10일 이후에 측정되거나 (Ahn & Shin, 2007) 알코올 (Reynolds, Banerjee, & Meek, 2005) 혹은 Chlorhexidine (Lashkari, Chow, & Godambe, 2012 …”

Prävention von Gefäßkatheter-assoziierten Infektionen bei Früh- und Neugeborenen

“…Povidonjod interferiert mit der Synthese von Schilddrüsenhormonen und ist daher kontraindiziert [111,112]. Auch Chlorhexidin (CHX) in wäss-riger Lösung (CHX-Gluconat 2 %) kann bei sehr unreifen Frühgeborenen schwere Hautreaktionen verursachen [113,114]. Verbände, die lokal CHX an der Eintrittsstelle eines PICC freisetzen, können bei Früh-und Neugeborenen schwerwiegende lokale Unverträglichkeiten auslösen [115,116].…”