Aqueous Crystallization Strategy for Metastable h‐MoO₃ Crystals with Polyvinylpyrrolidone Induction

Abstract

Micro‐sized hexagonal‐phase MoO3 (h‐MoO3) crystals were successfully prepared by a polyvinylpyrrolidone (PVP) induced aqueous route with (NH4)6Mo7O24·4H2O and HCl as raw materials. The linear structure of the PVP molecules matches the tunnel structure of the metastable h‐MoO3 crystals and, thus, enables the induced crystallization in an aqueous solution even at near‐ambient temperatures (40–50 °C). The achieved h‐MoO3 crystals have good monodispersity with a one‐dimensional (1D) outline and hexagonal cross‐section. The H+/Mo ratio is another key factor for the synthesis of h‐MoO3 crystals. The photochromic properties of PVP‐dependent samples of h‐MoO3 crystals were studied under natural sunlight irradiation.

Induction of DNA Damage and G2 Cell Cycle Arrest by Diepoxybutane through the Activation of the Chk1-Dependent Pathway in Mouse Germ Cells

“…46 Guo et al showed that ATM (pSer-1981) and Chk1 (pSer-345) activations were concomitant with cucurbitacin B induced G 2 /M arrest in human lung adenocarcinoma epithelial A549 cells, but they did not observe ATR (pSer-428) and Chk2 (pThr-68) activations. 47 In our study, a significant increase of the phosphorylation of Chk1 on Ser-345 after DEB exposure was observed, whereas the phosphorylation of Chk2 on Thr-68 was not affected, which is consistent with the result of a previous study. 47 We also found that the increased expression of phosphorylates Cdc25c and Cdc2, which are downstream factors of the Chk1 signal cascade, in response to DNA damage.…”

“…47 In our study, a significant increase of the phosphorylation of Chk1 on Ser-345 after DEB exposure was observed, whereas the phosphorylation of Chk2 on Thr-68 was not affected, which is consistent with the result of a previous study. 47 We also found that the increased expression of phosphorylates Cdc25c and Cdc2, which are downstream factors of the Chk1 signal cascade, in response to DNA damage. To establish the role of Chk1 in DEB-mediated G 2 phase arrest in GC-2 cells, Chk1 siRNA was transfected to knock down Chk1 gene expression, which efficiently reversed downstream effectors such as pCdc25c (Ser 216) and p-Cdc2 (Tyr 15).…”

Morphology‐controlled Synthesis of Molybdenum Oxide with Tunable Plasmon Absorption for Phothermal Therapy of Cancer

“…[28][29][30] Research work have indicated that molybdenum oxide (MoO 3 ) has various forms: one of them is the thermodynamic and stable phase of orthorhombic α-MoO 3 , [11][12][13] and the others are metastable phases of monoclinic β-MoO 3 , [31] hexagonal h-MoO 3 . [32,33] The conversion of the stoichiometric MoO 3 into nonstoichiometric oxygen deficiency molybdenum oxide (MoO 3-x ) since that the becoming of heterovalent heteroatoms or lattice vacancies or lattice vacancies [34,35] have excellent advantages, such as electrical conductivity, catalytic properties, optical properties and so on, to be achieved by controlling and adjusting the valence state of molybdenum element [36,37] which will be applied in various science fields. Furthermore, increased with oxygen hole, the color of MoO 3-x arrange from blank to obvious blue with an valid LSPR absorption in NIR.…”

UV Photochromism in Transition Metal Oxides and Hybrid Materials

“…[ 186 ] This is because tunnel and layered structures in metastable MoO 3 are generally more spacious in the crystal structure and this contributes to accelerated electron–hole migration under UV irradiation. [ 187 ] Tunnel structures present in metastable MoO 3 also allow more ions to intercalate, which promotes efficient ion insertion/extraction and reduces potential barriers for ion diffusion, [ 188 ] which is regarded as an improved photochromic activity compared to the orthorhombic α‐MoO 3 . For example, h‐MoO 3 and α‐MoO 3 films fabricated using ion exchange and chemical deposition exhibit fluorescence emission peaks at 440 and 630 nm (h‐MoO 3 ) and at 440 nm (α‐MoO 3 ).…”