Aqueous humour glucose concentration in cataract patients and its effect on the lens

Corneal autofluorescence in relation to permeability of the blood-aqueous barrier in diabetic patients with clinically significant macular edema and in an age-matched control group

“…19 Furthermore, the concentration of glucose in the anterior chamber is only 50-75% of that in plasma even in diabetic patients. 8,9 It seems thus unlikely that the concentration of glucose will not increase when there is a breakdown of the blood-aqueous barrier. The increase in aqueous humour glucose due to a breakdown of the bloodaqueous barrier may, however, be small compared to the increase seen as a consequence of the persistent hyperglycemia in patients with diabetes mellitus.…”

“…The ratio between aqueous humour glucose and blood glucose concentrations is 0.5 to 0.75. 8,9 Hypothetically, the concentration of glucose in the aqueous humour relative to the concentration of glucose in the blood should increase if there is more leakage through the blood aqueous barrier. Since the only known rate-limiting step in formation of advanced glycation end products is the concentration of glucose, corneal autofluorescence is consequently expected to increase when there is a breakdown of the blood aqueous barrier.…”

Corneal endothelial alterations in alcohol dependence syndrome

“…As a result, there might be a fall in aqueous glucose level, as aqueous humour maintains a specific concentration of glucose (60% of blood glucose concentration) in comparison to the blood glucose level 18. Since glucose is one of the important nutrients of corneal endothelium, there is a possibility that the reduced aqueous glucose level might result in damage to the corneal endothelium.…”

Calcification of a hydrophilic acrylic intraocular lens: Clinicopathological report

“…The normal readings are 0.23 to 1.3 g/L for protein, 17 0.45 to 2 mmol/L for calcium in patients with cataract, 18 2.19 G 0.47 mg/dL for phosphate, 19 166.67 to 446.4 umol/L for uric acid in normal subjects, 150 to 210 umol/L in patients with cataract or glaucoma, 20-22 and 3.2 mmol/L for glucose in normal subjects and 7.9 mmol/L in diabetic patients. 23 Although the analyses of aqueous and blood were normal, the mechanisms initiating the calcification may have occurred earlier.…”