Aqueous microwave chemistry: a clean and green synthetic tool for rapid drug discovery

Abstract

The development of "Greener Organic Chemistry" is due to the recognition that environmentally friendly products and processes will be economical in the long term as they circumvent the need for treating 'end-of-the-pipe' pollutants and by-products generated by conventional synthesis. The fundamentals and significant outcomes of microwave-assisted organic synthesis in aqueous medium are summarized in this tutorial review, which have resulted in the development of relatively sustainable and environmentally benign protocols for the synthesis of drugs and fine chemicals.

Influence of Microwave Irradiation on Hydrolysis Reaction of Sunflower Oil in Aqueous Emulsion

“…This process mainly depends on the specific polarity of molecules. Since water is polar it has good potential to absorb microwaves and to convert them into heat energy, consequently accelerating the reactions in an aqueous medium as compared to results obtained using conventional heating [15]- [17].…”

Electromagnetic Field Transmission Characteristics in High Frequency by Particle Effect

“…It is well-known that the basic characteristics of materials often change such as higher boiling point 1) or higher speed chemical reaction or lower temperature chemical reaction 2,3) or another material creation, [4][5][6] when a high frequency electromagnetic field is applied to not only the organic substance but also the ceramics and the metal.…”

Microwave-promoted synthesis of cyclic imides

“…Employment of this novel strategy has given rise to the so-called "Green Chemistry", and the application of such strategy is now fostered to minimize the use of nonrenewable resources as well as polluting solvents, which are known to generate secondary toxic products, and to reduce the emission of harmful gases. 62 In the context of the Green Chemistry, 65,66 solvent-free 67,68 and water-mediated [69][70][71] MW-assisted reactions acquire a relevant role.…”