Aqueous photocatalytic oxidation of prednisolone

Abstract

Abstract:© Versita Sp. z o.o. Keywords: Photocatalysis • Corticosteroid • Doped titania • Oxidation pathway • TiO Research ArticleThe research into the aqueous photocatalytic oxidation of the anti-inflammatory drug prednisolone was undertaken with P25 titanium dioxide (Evonik) and visible light-sensitive sol-gel synthesized titania-based photocatalysts containing carbon, sulphur, and iron. Possible prednisolone photocatalytic oxidation reaction pathways were proposed based on a number of oxidation by-products determined in the present study. The prednisolone adsorption properties, effects of initial prednisolone concentration, pH, usual wastewater matrix admixtures, like carbamide and sucrose, were studied. The nontoxicity of doped catalysts towards Tetrahymena thermophila, a ciliate protozoa present in the activated sludge, indicated their lower oxidative ability compared to P25, but also implied their potential application in pre-treatment of toxic hazardous materials under VIS or solar radiation before the biological degradation stage.

Elimination of persistent emerging micropollutants in a suspended-bed photocatalytic reactor: influence of operating conditions and combination with aerobic biological treatment

“…The results are also in agreement with the data on photocatalytic oxidation of these pharmaceuticals in P25 slurry, where doxycycline and prednisolone were degraded faster than amoxicillin and sulfamethizole due to their different molecular structures and higher adsorption affinities to TiO 2 . [6][7][8][9] Higher adsorption affinities of the pollutants were accompanied by higher photocatalytic oxidation efficiencies, presumably due to direct reactions on the surface of TiO 2 . Higher adsorption on the coated-bed materials is a prerequisite for superior elimination of pollutants by the combination of photocatalytic oxidation and adsorptive removal processes.…”

“…in combination with biological treatment. [6][7][8][9] Bio-oxidation of antibiotics has been previously studied; for example, [10][11][12][13][14] it was found that adsorption is the primary mechanism for removal of tetracyclines in an activated sludge system, while biodegradation appears to be dependent on operation conditions and has been reported to remove antibiotics from negligible amounts to rates up to 63%. [15][16][17][18] The photocatalytic oxidation of tetracycline as a pretreatment method resulted in the reduction of toxicity of treated antibiotic solution; however, further optimization of the experimental conditions is necessary to generate more biodegradable by-products.…”

An Overview of the Glucocorticoids’ Pathways in the Environment and Their Removal Using Conventional Wastewater Treatment Systems

“…Adsorption with nano particles, e.g., Fe (VI) nanoparticle adsorption Highly Effective (80-99%) [95] Adsorption with activated carbon Highly Effective (98%) [150][151][152] Sorption Effective (98%) [108,117] Photocatalysis (µg/liter levels) Effective (>95%) [158][159][160][161][162] Chlorination Activated sludge systems combined with chlorination in tertiary treatment has been effective (95%) [108] Combination of reverse osmosis and micro-filtration Depends on the concentration of GCs. (56-90%) [163] Advanced oxidation processes (Ozone, UV/H 2 O 2 , photo-Fenton processes)…”

Removal of 26 corticosteroids, potential COVID-19 remedies, at environmentally relevant concentrations in water using UV/free chlorine, UV/monochloramine, and UV/hydrogen peroxide

“…5 Moreover, most of previous studies focused on a limited list of target CSs (5-6 CSs) at high method detection limits (>1 ng L −1 ). [21][22][23][24] To date, no comprehensive studies are available dealing with the transformation processes of a large group of CSs at environmental concentrations during UV-based AOPs. Systematic investigations on CS behavior during UV-based AOPs through sensitive analytical methods are urgently needed.…”