Aqueous polyaromatic receptors for biomolecules with high selectivity

Caged bulky organic dyes in a polyaromatic framework and their spectroscopic peculiarities

“…1b ) shows efficient/selective binding abilities toward various synthetic compounds 8 as well as biomolecules in aqueous solution, through efficient hydrophobic effect and multipoint π–π/CH–π/hydrogen-bonding interactions. 6,9 However, like other coordination cages reported previously, 4 capsule 2 exhibits no binding ability toward synthetic dyes with multiple bulky substituents , whose sizes are larger than that of the cavity ( d = 1.2 nm), owing to the closed spherical framework ( Fig. 1d ).…”

“…Notably, the emission quantum yield of 4a ( Φ F = 52%) was enhanced by 1.2-fold within 1 , in contrast to the majority of previous coordination hosts, which quench guest fluorescence to a large degree, owing to the heavy metal effect and host–guest π-stacking/CT interactions. 4,6 The emission properties of 1·4a were maintained for at least 7 d at ambient temperature in the dark (Fig. S19a†).…”

“…Host functions of the polyaromatic cavities of coordination capsules have been highlighted recently. 6,7 For example, the closed polyaromatic cavity of M 2 L 4 capsule 2 (Fig. 1b) shows efficient/selective binding abilities toward various synthetic compounds 8 as well as biomolecules in aqueous solution, through efficient hydrophobic effect and multipoint π–π/CH–π/hydrogen-bonding interactions.…”

Water-Soluble Self-Assembled Cage with Triangular Metal–Metal-Bonded Units Enabling the Sequential Selective Separation of Alkanes and Isomeric Molecules

“…Since the first serendipitous isolation of a self-assembled tetrahedral coordination cage, the development of discrete three-dimensional (3D) coordination cages, − especially water-soluble molecular cages comprising accessible cavities, has attracted a great deal of research attention. − Such molecular cages adopt different geometries and include accessible hydrophobic inner spaces; indeed, these species have found widespread use in the selective encapsulation, separation, and release of a variety of guest molecules, as well as in the promotion of chemical reactions in the aqueous phase. − The design and development of new systems that can distinguish between structurally similar compounds would provide new applications for self-assembled tetrahedral coordination cages, especially in the context of the separation of isomeric molecules.…”

Shifting the Triangle–Square Equilibrium of Self-Assembled Metallocycles by Guest Binding with Enhanced Photosensitization

“…Coordination self-assembly has been evolving immensely in recent years due to the captivating performance displayed by supramolecular architectures in the nanoscopic dimensions . These structures are useful for designing materials that are capable of exploring applications in sensing, catalysis, guest encapsulation, drug delivery, stabilization of sensitive species, etc .…”