Aqueous Shunts in Glaucoma

Minckler, Don S.; Francis, Brian A.; Hodapp, Elizabeth; Jampel, Henry D.; Lin, Shan; Samples, John R.; Smith, Scott D.; Singh, Kuldev

doi:10.1016/j.ophtha.2008.03.031

Cited by 263 publications

(105 citation statements)

References 42 publications

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“…Glaucoma drainage implants (GDIs) have become a valuable tool for the surgical management of refractory glaucoma [1,2]. GDIs have been demonstrated to be effective in reducing intraocular pressure (IOP) and are especially indicated in cases with high risk of failure after filtering procedures [3,4].…”

Section: Introductionmentioning

confidence: 99%

A Review of the Ahmed Glaucoma Valve Implant and Comparison with Other Surgical Operations

et al. 2017

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The Ahmed glaucoma valve (AGV) is a popular glaucoma drainage implant used for the control of intraocular pressure in patients with glaucoma. While in the past AGV implantation was reserved for glaucoma patients poorly controlled after one or more filtration procedures, mounting evidence has recently encouraged its use as a primary surgery in selected cases. AGV has been demonstrated to be safe and effective in reducing intraocular pressure in patients with primary or secondary refractory glaucoma. Compared to other glaucoma surgeries, AGV implantation has shown favorable efficacy and safety. The aim of this article is to review the results of studies directly comparing AGV with other surgical procedures in patients with glaucoma.

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Section: Introductionmentioning

confidence: 99%

A Review of the Ahmed Glaucoma Valve Implant and Comparison with Other Surgical Operations

et al. 2017

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“…During the past decade, the use of GDDs for controlling IOP in various forms of glaucoma has increased [23-25]. However, there remains concern and significant controversy regarding glaucoma surgery in eyes with an intraocular tumor due to fear of both orbital and systemic tumor dissemination, increasing metastatic risk [1, 9, 10, 13, 15, 26].…”

Section: Discussionmentioning

confidence: 99%

Outcomes of Glaucoma Drainage Device Surgery in Eyes with Treated Uveal Melanoma

Fatehi¹,

McCannel²,

Giaconi³

et al. 2018

Ocul Oncol Pathol

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Aim: We report patient safety and intraocular pressure (IOP) control after placement of a glaucoma drainage device (GDD) in eyes with a history of treated malignant uveal melanoma. Methods: A retrospective review of the records of patients with uveal melanoma was performed. Outcomes were local tumor recurrence, rate of metastases, and tonometric success, based on survival curves, defined as IOP < 21 mm Hg. Results: Eleven eyes with choroidal melanoma, 4 with iris melanoma, and 1 with ciliary body melanoma were followed for a median (interquartile range) of 2.1 (1.1–3.2) years. Two subjects developed liver metastases; one had monosomy 3 and tumor gene expression profile class 2. The other case with ciliary body melanoma was negative for monosomy 3. There were no cases of local treatment failure. Mean preoperative IOP decreased from 30.5 ± 7.7 to 15.9 ± 8.1 mm Hg at 1 year after surgery (1-year success rate 80%). Conclusions: Our case series with a median follow-up of 2 years shows that placing a GDD in patients with treated uveal melanoma does not expose patients to greater risk of local or extraocular recurrence. A larger series and longer follow-up time are required to fully evaluate the safety of GDDs in this clinical scenario.

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“…The glaucoma drainage implants [49,53] used most widely in clinical practice over the last decade have been the nonvalved single-or double-plate Molteno (Molteno Ophthalmic Ltd, New Zealand), the valved Ahmed (New World Medical, USA), the Krupin (Hood Laboratories, USA) and the non-valved Baerveldt implant (Advanced Medical Optics, USA) (Fig. 1).…”

Section: Subconjunctival Glaucoma Drainage Implantsmentioning

confidence: 99%