2019
DOI: 10.3390/mi11010027
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Arced Multi-Nozzle Electrospinning Spinneret for High-Throughput Production of Nanofibers

Abstract: The stable and continuous ejection of multiple jets with high densities is the key to the application of electrospinning technology. An arced multi-nozzle spinneret was designed to increase the production efficiency of electrospinning. The distribution of the electrical field was simulated to optimize the nozzles’ distribution of the spinneret. When the nozzles were arranged in an arc array, a relatively uniform electrical field could be obtained, which was beneficial for the weakening of electrical interferen… Show more

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Cited by 22 publications
(8 citation statements)
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“…Attaching a metal needle to the end of the syringe, and charging (or grounding) the needle fulfils the basic feed requirements for electrospinning and is often as far as researchers need to go for proof-of-concept studies [18][19][20][21][22][23], or basic morphology work [24][25][26][27][28]. An extension of this method is to utilize multiple needles on the same syringe pump to increase the material throughput and the electrospinning footprint on the collector [29][30][31].…”
Section: Feedmentioning
confidence: 99%
“…Attaching a metal needle to the end of the syringe, and charging (or grounding) the needle fulfils the basic feed requirements for electrospinning and is often as far as researchers need to go for proof-of-concept studies [18][19][20][21][22][23], or basic morphology work [24][25][26][27][28]. An extension of this method is to utilize multiple needles on the same syringe pump to increase the material throughput and the electrospinning footprint on the collector [29][30][31].…”
Section: Feedmentioning
confidence: 99%
“…Therefore, different arrangements may be applied to the needles such as one-dimensional linear configuration or two-dimensional configurations such as elliptical, circular, triangular, square and hexagonal [ 65 , 74 ]. An arced multi-nozzle spinneret was designed to increase the production efficiency of electrospinning, resulting in relatively uniform electrical fields which in turn decreases the electrical interference of the needles and subsequently improves nanofiber quality [ 75 ]. The following are some examples for applying this technology for drug delivery and the pharmaceutical industry: an electro-spun formulation containing galactosidase as a model biopharmaceutical drug has been successfully developed through using scaled-up electrospinning experiments of a lab-scale, high-speed electrostatic spinning (HSES) setup consisting of a circular-shaped, stainless steel spinneret, equipped with eight orifices, and connected to a high-speed motor.…”
Section: Up-scaling Of Nanofiber Productionmentioning
confidence: 99%
“…The electrospun nanofibrous membrane was fabricated by the previous reported method of multi-jet electrospinning with sheath gas [49][50][51][52], as shown in figure 1. The sheath gas in the laminar flow is helpful to overcome the electrical interferences among nozzles and to promote the stability of multijet electrospinning process.…”
Section: Preparation Of Nanofibrous Membranementioning
confidence: 99%