Innovative, non-invasive, digital, and cost-effective instruments for systematic inventory, monitoring and promotion are a valuable resource for managing tangible and intangible cultural heritage. Due to its powerful and effective inventory and analysis potential, which allows supporting central and local entities responsible for cultural heritage management, Geographic Information Systems (GIS) have proven to be an appropriate information technology for developing these kinds of instruments. Given the above, this work aims to introduce a GIS-based instrument to support inventorying, safeguarding, tourism, and cultural promotion of the traditional Portuguese glazed tile (‘azulejo’, in Portuguese) to raise general awareness of the importance of this unique Portuguese heritage. To the best of the authors’ knowledge, there is no other instrument available with inventory and safeguarding management functions that is accessible and affordable, developed to be used at a municipal level and that contributes to the enrichment of the cultural and tourist information. Information from 70 tile works located in the Portuguese city of Covilhã was used to test the proposed GIS tool, resulting in a georeferenced alphanumeric, graphical, image and drawing inventory and in three pedestrian routes for touristic and cultural heritage promotion. The results were validated by both the research team and the municipality of Covilhã, foreseeing its expansion and daily use in the management of the heritage of the traditional Portuguese glazed tile. The proposed instrument can be replicated in other locations and easily implemented and managed by municipalities or institutions dealing with the protection of cultural heritage.