Are anticonvulsants a satisfactory alternative to opiate analgesia in patients experiencing pain with Guillain-Barre syndrome?

McDouall, S F

doi:10.1136/adc.2004.054510

Cited by 5 publications

(4 citation statements)

References 5 publications

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“…But children, especially manijky of those in this cohort, would be too young to selfreport, and those old enough may not be able to self-report for the initial period due to being sedated and/or ventilated [28]. The autonomic dysfunction which occurs in patients with Guillain-Barré syndrome would be a significant confounding factor when considering pain rating tools that rely on physiological measures [28]. Inadequate measurement and assessment of pain during the study period limits definitive or useful comment on the degree of pain experienced by these children.…”

Section: Discussionmentioning

confidence: 99%

“…Self-reporting is considered the most reliable method, especially in the setting of chronic pain [32,34,33]. But children, especially manijky of those in this cohort, would be too young to selfreport, and those old enough may not be able to self-report for the initial period due to being sedated and/or ventilated [28]. The autonomic dysfunction which occurs in patients with Guillain-Barré syndrome would be a significant confounding factor when considering pain rating tools that rely on physiological measures [28].…”

Section: Discussionmentioning

confidence: 99%

“…Whilst AEDs such as carbamazepine, gabapentin and pregabalin are used for pain control, there is a lack of class one studies [19,20,22,23,24]. Small study size trials support the efficacy and safety of these drugs as analgesics, and there are reports that they are at least as effective as opioids for neuropathic pain relief with the additional advantage of reducing opioid requirements [25,26,27,28]. This study reviewed the trends in the assessment and management of pain in children admitted to a tertiary centre in sub-Saharan Africa with Guillain-Barré Syndrome.…”

Section: Introductionmentioning

confidence: 99%

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The assessment and management of pain in children with Guillain-Barré Syndrome in a sub-Saharan setting.

Hutton

Wilmshurst

2019

JICNA

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Introduction: Neuropathic pain is challenging to manage in children compounded by inappropriate assessment tools. The lack of evidence-based pain control guidelines for children results in clinicians deferring to expert opinion and personal preference. Children with Guillain-Barré Syndrome are particularly at risk is of neuropathic pain. Objectives and Methods: This is a retrospective study of children with Guillain-Barré Syndrome who were admitted to Red Cross War Memorial Children's Hospital, Cape Town, South Africa over a 10 year period. The study reviewed their pain assessment and management practice. Results: Eighty-four children were identified with Guillain-Barré Syndrome. 76% had symptoms of pain and 53% had breakthrough pain reported. Standardised pain rating scales were used in 3 patients. A mean of 2.7 analgesics were used per patient. Carbamazepine and gabapentin, were utilised in 27 and 20 patients respectively. The use of gabapentin increased 73% per annum from 2009. There was no statistical difference between these two groups for length of hospital stay or long-term disability. Conclusion: This study identified a significant gap in the assessment of pain in children with Guillain-Barré Syndrome. Tools to adequately assess pain are needed, especially in immobile and non-verbal children. Management of pain revealed a high use of adjuvant drugs. The dramatic increase in the use of gabapentin related to clinician preference and was not supported by any evidence. Clinical outcomes for both the carbamazepine and the gabapentin group were no different.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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The assessment and management of pain in children with Guillain-Barré Syndrome in a sub-Saharan setting.

Hutton

Wilmshurst

2019

JICNA

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“…Antiepilépticos como gabapentina y carbamacepina, así como los opioides en general, actualmente son fármacos con pobre evidencia para el tratamiento del dolor en estos pacientes 24 , sin embargo, tienen evidencia suficiente en otros tipos de dolor neuropático, lo que permite utilizarlos como alternativa de tratamiento 25 .…”

Section: Rev Col Med Fis Rehabunclassified

El dolor en el síndrome de Guillain - Barré ¿un síntoma subtratado?

Gutiérrez

Arenas

Antolinez

2015

Rev Col Med Fis Reh

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RESUMENEl síndrome de Guillain -Barré (SGB) es una polirradiculoneuropatía de inicio agudo y progresión rápida, caracterizada en ocasiones por desmielinización y en otras por daño axonal primario (inflamatorio-tó-xico) en gran parte reversible, que afecta principalmente los nervios motores, aunque también puede afectar los nervios sensitivos 1 . Alcanza su intensidad máxima dentro de cuatro semanas con debilidad, arreflexia, afectación de pares craneales y hasta falla ventilatoria, el tratamiento se realiza con inmunoglobulina intravenosa (Ig IV) o con plasmaféresis, es una patología que en todas sus variantes puede causar un dolor agudo y crónico 2 .Se presenta el caso de una paciente de 53 años con un SGB variante, neuropatía axonal motora y sensitiva aguda (AMSAN) y dolor lumbar y neuropático secundario, se relata su tratamiento médico y una revisión de la literatura del tratamiento del dolor en SGB.Palabras clave: Síndrome de Guillain -Barré, dolor musculo esquelético, dolor neuropático, opioides, gabapentinoides. ABSTRACTGuillain-Barré syndrome (GBS) is an acute polyradiculoneuropathy start and rapid progression, sometimes characterized by demyelination and axonal damage other by primary (inflammatory-toxic), largely reversible, which mainly affects the motor nerves, although it may also affect sensory nerves 1 . Reaches its maximum intensity within four weeks, the treatment is performed with intrave- Rev Col Med Fis Rehab 2016; 25(2): 156-162

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Inflammatory Neuropathies

Sladky¹,

Ashwal²

2012

Swaiman's Pediatric Neurology

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Are anticonvulsants a satisfactory alternative to opiate analgesia in patients experiencing pain with Guillain-Barre syndrome?

Cited by 5 publications

References 5 publications

The assessment and management of pain in children with Guillain-Barré Syndrome in a sub-Saharan setting.

The assessment and management of pain in children with Guillain-Barré Syndrome in a sub-Saharan setting.

El dolor en el síndrome de Guillain - Barré ¿un síntoma subtratado?

Inflammatory Neuropathies

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