Are calcium antagonists safe?

Hamstring tendon autograft better than bone–patellar tendon–bone autograft in ACL reconstruction—a cumulative meta-analysis and clinically relevant sensitivity analysis applied to a previously published analysis

“…"A metaanalysis is like a Mediterranean bouillabaisse-in concert, all ingredients will enhance its delightful flavour but, no matter how much fresh fish is added, one rotten fish will make it stink." (Messerli 1985, Hopayian 2001.…”

The Effectiveness of Cognitive Therapy for Schizophrenia: What Can We Learn from the Meta-Analyses?

“…Meta-analyses may be imperfect, even from the most reliable of sources [30]. As another commentator put it when criticising conclusions of a meta-analysis in cardiology: ‘a metaanalysis is like a Mediterranean bouillabaisse – in concert, all ingredients will enhance its delightful flavour but, no matter how much fresh fish is added, one rotten fish will make it stink’ [31]. …”

Has the role of calcium channel blockers in treating hypertension finally been defined?

“…These reports created a great deal of anxiety and apprehension among practicing physicians and patients, who became very concerned about using calcium channel blockers for the treatment of hypertension. These reports also incited major controversy and criticism from the academic and medical community in the United States and elsewhere [14][15][16][17]. The reasons for this criticism were that these reports were based on retrospective case-control studies, which are very difficult to analyze, and also used older, short-acting calcium channel blockers, which cause acute drops in blood pressure that may lead to coronary "steal," as well as depriving vulnerable sections of myocardium critical nutrient blood flow due to coronary artery obstruction.…”