2020
DOI: 10.1002/pon.5499
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Are common delirium assessment tools appropriate for evaluating delirium at the end of life in cancer patients?

Abstract: Objectives: The objectives of this study are to investigate how many advanced cancer patients became unconscious or non-communicative after pharmacological treatment for delirium, and to explore whether existing delirium assessment tools can successfully evaluate its severity at the end of life. Methods: This was a secondary analysis of a registry study that examined the efficacy and safety of antipsychotics for advanced cancer patients with delirium. A total of 818 patients were recruited from 39 specialized … Show more

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Cited by 8 publications
(3 citation statements)
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“…However, these numbers may be overestimated due to the lack of tools to identify delirium at the end of life. The normal dying process may trigger false positives using the available delirium screening tools for hypoactive delirium [39,59]. According to the literature, hyperactive delirium is the main indication for palliative sedation [7].…”
Section: Discussionmentioning
confidence: 99%
“…However, these numbers may be overestimated due to the lack of tools to identify delirium at the end of life. The normal dying process may trigger false positives using the available delirium screening tools for hypoactive delirium [39,59]. According to the literature, hyperactive delirium is the main indication for palliative sedation [7].…”
Section: Discussionmentioning
confidence: 99%
“…Because both the original and the Japanese versions of DRS-R98 did not investigate the cutoff score for delirium severity determination (Trzepacz et al, 2001; Kato et al, 2010), this result could be a new finding. However, the DRS-R98 severity scale has been suggested as unsuitable for evaluating end-stage patients’ delirium because of unconsciousness or non-communicativeness (Uchida et al, 2020). This inappropriateness might also affect the association between the baseline severity score and that on day 3.…”
Section: Discussionmentioning
confidence: 99%
“…The present study is a secondary analysis of Phase-R, a multicenter and prospective observational study (Okuyama et al, 2019;Maeda et al, 2020Maeda et al, , 2021Matsuda et al, 2020;Uchida et al, 2020). Data were collected at 14 palliative care units certified by the Hospice Palliative Care Japan and 9 psycho-oncology settings of tertiary cancer care hospitals or university hospitals across Japan from September 2015 to May 2016.…”
Section: Phase-r Studymentioning
confidence: 99%