Are dietary supplements and nutraceuticals effective for musculoskeletal health and cognitive function? A scoping review

Abstract

This scoping review showed that selected micronutrients in adequate doses might have an ancillary role in musculoskeletal health and cognitive functions in older people.

Italy's nutraceutical industry: a process and bioeconomy perspective into a key area of the global economy

“…The industry, however, is aware of the need to support and promote an evidence‐based approach. For example, in 2017, a joint industry‐academy‐clinical research team (the Italian Study Group on Healthy Aging by Nutraceuticals and Dietary Supplements) published the outcomes of a scientific literature search that aimed to identify the most relevant positive study for each micronutrient included in dietary supplements and nutraceuticals commercialized in Italy in each of three selected areas (bone, skeletal muscle, and cognitive function) …”

“…The team found 12 relevant positive studies (one international society guidelines / recommendation, one systematic review, seven randomized controlled trials, and three prospective cohort studies), with only 16 micronutrients (beta‐alanine, calcium, creatine, fluorides, leucine, magnesium, omega‐3 fatty acids, potassium, vitamin B 6 , vitamin B 9 , vitamin B 12 , vitamin C, vitamin D, vitamin E, vitamin K2, and zinc) supported by scientific evidence for improving musculoskeletal health and / or cognitive function in older people …”

“…For example, in 2017, a joint industry-academy-clinical research team (the Italian Study Group on Healthy Aging by Nutraceuticals and Dietary Supplements) published the outcomes of a scientific literature search that aimed to identify the most relevant positive study for each micronutrient included in dietary supplements and nutraceuticals commercialized in Italy in each of three selected areas (bone, skeletal muscle, and cognitive function). 14 The team found 12 relevant positive studies (one international society guidelines / recommendation, one systematic review, seven randomized controlled trials, and three prospective cohort studies), with only 16 micronutrients (beta-alanine, calcium, creatine, fluorides, leucine, magnesium, omega-3 fatty acids, potassium, vitamin B 6 , vitamin B 9 , vitamin B 12 , vitamin C, vitamin D, vitamin E, vitamin K2, and zinc) supported by scientific evidence for improving musculoskeletal health and / or cognitive function in older people. 14 Two selected nutraceutical products representing renowned and emerging nutraceuticals, omega-3 lipids and olive biophenols, show how companies are increasingly using clinical studies to substantiate claims and to provide customers with the required data supporting the health benefits that are claimed.…”

Comparing the Effects of Zinc Supplementation as Adjunct to the Conventional Therapy and Placebo on Morbidity in Children with Pneumonia Between Ages 1 Year to 5 Years

“…Zinc deficiency has been known since the 1960s [11]. Zinc may have an important protective role in the respiratory epithelium and deficiency may enhance airway inflammation and epithelial damage [12], impairs many cellular and humoral immune functions including lymphocyte number and function [13]. Animals had decreased inflammation and cellular damage in the presence of zinc [11].…”

The Journal of Cachexia, Sarcopenia and Muscle stays the front‐runner in geriatrics and gerontology

“…Iolascon G Are dietary supplements and nutraceuticals effective for musculoskeletal health and cognitive function? A scoping review Review 12 200 17…”