Are lipid profile, body mass index, waist circumference, and blood pressure of depressed elderly patients different from healthy subjects?

Amini, Shirin; Shirali, Saeed; Jafarirad, Sima; Ehsani, Hajar; Mohseni, Houra; Bargard, Mehdi Sayah

doi:10.4103/ijpvm.ijpvm_372_17

Cited by 6 publications

(1 citation statement)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Abnormalities in the lipid profile have been found to be a significant complication that predisposes to a variety of diseases, including cardiovascular disease, diabetes, and obesity. In the current study, as shown in Figure 1, the finding is consistent with the work of other studies in this area linking lipid profile with BMI [18][19][20][21][22]. It also seems possible that the impacts of obesity on lipid metabolism are depending on the distribution of adipose tissues.…”

Section: Discussionsupporting

confidence: 92%

A Comparative Biochemical Study Between Patient’s Obese and Healthy

Salman

Saifullah

2023

IHJPAS

View full text Add to dashboard Cite

Objectives: Obesity rates have increased globally with increase in the incidence of comorbidities especially type 2 diabetes mellitus. A cross-sectional study was conducted on healthy obese adults to estimate: (i) comparisons of anthropometric indicators, lipid profile, and glycemic profile in obese compared with non-obese, and (ii) the association of anthropometrics and lipid profile with glycemic profile in obese adults. Methods: The study includes 120 individual with aged ranged (25 – 55) years were enrolled in this study. They were divided into two groups: group one (G1) consist of 90 patients with a body mass index (BMI) of more than 25 kg/m2. Group two (G2) of 30 healthy adults as a control group with (BMI) of less than 25 kg/m2.waist circumference (WC), hip circumference (HC), and waist/hip ratio (WHR) as anthropometric indicators, and fasting serum lipid profile, glycated hemoglobin (HbA1c), and Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) as biochemical variables were assessed. Statistical significance (α) was set at (p<0.05).Results: Based on independent samples T-test analysis acted as a significant comparison between non-obese and obese groups, anthropometrics and biochemical variables exhibited highly significant higher in obese compared with non-obese. Also, a positive significant correlation was found between WC and WHR with both of HOMA-IR and HbA1c. Finally, a positive significant association of HOMA-IR with triglycerides (TG), total cholesterol (TC), very low-density lipoprotein cholesterol (VLDL-C), low-density lipoprotein cholesterol (LDL-C) except for high-density lipoprotein cholesterol (HDL-C), no significance was found as well as HbA1c showed only positive significant association with LDL-C. In conclusion, the present study demonstrated that WC was the strongest indicator for increasing HOMA-IR than WHR. Also, this study revealed that abnormalities in lipid profile in obese participants have shown strong positive association with HOMA-IR, particularly LDL-C.

show abstract

Section: Discussionsupporting

confidence: 92%