BACKGROUNDPsoriasis is an immune-mediated disease that manifests predominantly in the
skin, although systemic involvement may also occur. Although associated
comorbidities have long been recognized and despite several studies
indicating psoriasis as an independent risk factor for cardiovascular
events, little has been done in general medical practice regardind
screening. In the United States, less than 50% of clinicians are aware of
these recommendations.OBJECTIVETo identify the prevalence of these comorbidities in 296 patients followed up
at a university dermatology clinic.METHODSSystematically investigated comorbidity frequencies were compared with
general practitioners' registry frequencies. Clinical features correlated
with comorbidities were also investigated.RESULTSHigh prevalences of systematically investigated comorbidities such as
hypertension (30%) and dyslipidemia (26.5%) were documented. Conversely,
data from general practitioners' records showed that 33% of dyslipidemia
cases were undiagnosed and indicated possible underdiagnosis of some
comorbidities. Furthermore, an association was found between: the number of
comorbidities and psoriasis duration, age and high body mass index an
association was found between the number of comorbidities and psoriasis
duration, age, high body mass index, waist circumference or waist-to-hip
ratio. (p<0.05).CONCLUSIONDisease duration, age and high body mass index, waist circumference or
waist-to-hip ratio are possible criteria for choosing which patients should
be screened for comorbidities. Underdiagnosis of comorbidities by general
practitioners highlights the need for a multidisciplinary approach in
psoriasis management.