Are the Diagnosis and Treatment of Neuropsychiatric Co-morbidity in Multiple Sclerosis Still in Their Infancy?

Abstract

Four clinical dimensions can be impaired in multiple sclerosis (MS): neurological function, cognition, emotions and fatigue. Neurological impairment, cognitive deficits and fatigue are recognised to be part of the functional handicap and deterioration of quality of life in MS patients, while the effect of emotional impairment, which includes behavioural changes and decision-making difficulties, has been less precisely defined.