Are there any differences between age groups regarding colorectal surgery in elderly patients?

Bircan, Hüseyin Yüce; Koç, Bora; Ozcelik, Umit; Adaş, Gökhan; Karahan, Servet; Demi̇rağ, A

doi:10.1186/1471-2482-14-44

Cited by 26 publications

(26 citation statements)

References 11 publications

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“…Elderly is a very subjective term based mainly on the environmental culture of the patient. Elderly has been defined as a chronological age of ≥65 years of age, which has been further subdivided into early and late elderly for those who are 65 through 74 and over 75 years of age, respectively [ 8 ]. To the best of our knowledge, this is the first study about the outcome of colorectal surgery in elderly patients with comparison to a cohort group of nonelderly patients manually matched for BMI, ASA score, CCI and procedure performed (open vs. laparoscopic, elective vs. urgent).…”

Section: Discussionmentioning

confidence: 99%

Outcome of Colorectal Surgery in Elderly Populations

et al. 2016

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PurposeThe aim of this study is to investigate the impact of age on short-term outcomes after colorectal surgery in terms of the 30-day postoperative morbidity and mortality rates.MethodsThe subjects for the study were patients who had undergone colorectal surgery. Patients were divided into 2 groups according to age; groups A and B patients were ≥80 and <80 years old of age, respectively. Both groups were manually matched for body mass index, American Society of Anesthesiologists score, Charlson Comorbidity Index and procedure performed.ResultsA total of 200 patients, 91 men (45.5%) and 109 women (54.5%), were included in this retrospective study. These patients were equally divided into 2 groups. The mean ages were 85 years in group A (range, 80 to 104 years) and 55.3 years in group B (range, 13 to 79 years). The overall 30-day postoperative mortality rate was 1% of total 200 patients; both of these 2 patients were in group A. However, this observation had no statistical significance. No intraoperative complications were encountered in either group. The overall 30-day postoperative morbidity rate was 27% (54 of 200) for both groups. The 30-day postoperative morbidity rates in groups A and B were 28% (28 of 100) and 26% (26 of 100), respectively. However, these differences between the groups had no statistical significance importance.ConclusionAge alone should not be considered to be more of a contraindication or a worse predictor than other factors for the outcome after colorectal surgery on elderly patients.

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Section: Discussionmentioning

confidence: 99%

Outcome of Colorectal Surgery in Elderly Populations

et al. 2016

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“…Tolerability of surgery by elderly patients aged ≥ 80 years has been investigated in several studies and showed favorable outcomes in terms of postoperative mortality as compared with that of younger patients [11][12][13]. When "elderly" was defined as ≥ 75 years, the cancer-specific survival rate of elderly CRC patients receiving surgical treatment was not significantly different from that of younger patients [14][15][16].…”

Section: Discussionmentioning

confidence: 99%

Clinical characteristics and prognosis of elderly patients with colorectal cancer: comparison between surgical resection and supportive care

Kim

Soh

et al. 2020

Preprint

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Background Elderly colorectal cancer (CRC) patients tend to avoid standard treatment, especially curative surgical resection, because of concerns about surgical complications or underlying diseases. This study is intended to compare clinical characteristics and prognosis between patients who had undergone surgical resection and received supportive care, and to evaluate the usefulness of surgical treatment in elderly patients. Methods A total of 114 patients aged ≥80 years who were diagnosed with CRC were analyzed retrospectively. Of these patients, 73 patients underwent surgical resection for malignancy and 41 patients received supportive care. Clinicopathological factors and overall survival (OS) rates were compared. Results The s urgical resection group had better Eastern Cooperative Oncology Group (ECOG) performance status, American Society of Anesthesiologists (ASA) physical status, and a lower stage than did the supportive-care group. The 3-year OS rate of the surgical group was significantly higher than that of the supportive-care group (60.7% vs. 9.1%, p < 0.001). In extremely elderly patients (age ≥85 years), the surgical group showed a better 3-year OS rate than did the supportive-care group (73.9% vs. 6.3%, p < 0.001), although ECOG performance status and ASA physical status were not different. The post-operative mortality rate was 4.1%. In the analysis of risk factors related to survival, surgical resection was a good prognostic factor. Conclusions Surgical treatment in elderly CRC patients showed a survival benefit, even in the extremely elderly patients. Surgical resection for CRC in elderly patients can be considered to improve survival.

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“…For example, Bircan et al evaluated the impact of colorectal surgery on the short-term results and analyzed the factors that had the potential to influence these results in elderly patients, in a study conducted between January 2008 and December 2013. A total of 265 patients were enrolled and analyzed in that retrospective study (6). Among the patients who underwent surgery during the study period, 110 were between 60 and 69 years of age (group 1), 99 were between 70 and 79 years of age and 56 were ≥80 years of age.…”

Section: Discussionmentioning

confidence: 99%

“…However, previous studies have excluded patients in this age group. Furthermore, few authors have evaluated the short-and long-term outcomes of colorectomy for colorectal adenocarcinoma patients of ≥80 years of age (5,6). Thus, the short-term outcomes and long-term survival of elderly patients who undergo colorectomy for colorectal adenocarcinoma remain unclear.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of safety, feasibility and the long-term outcomes of colorectomy for colorectal adenocarcinoma in patients older than 80 years of age

Yukawa

Aoyama

Sato

et al. 2017

Molecular and Clinical Oncology

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Abstract. The short-and long-term outcomes of colorectomy for colorectal adenocarcinoma have not been fully evaluated in elderly patients. The present retrospective study investigated patients who underwent curative surgery for colorectal cancer at the Department of Surgery, Yokohama City University (Yokohoma, Japan). The patients were categorized into two groups: Elderly patients (70-79 years of age; group A) and extremely elderly patients (≥80 years of age; group B). The rates of surgical morbidity, surgical mortality, overall survival (OS), and recurrence-free survival (RFS) in the two groups were compared. A total of 191 patients were evaluated in the current study. Of these, 137 patients were included in group A, and 54 were included in group B. With the exception of the American Society of Anesthesiology physical status score, there were no significant differences in the preoperative clinicopathological outcomes of the two groups. The overall complication rates in groups A and B were 12.4 and 16.7%, respectively, and did not differ to a statistically significant extent (P= 0.440). In addition, surgical mortality was not observed in either group. The 5-year OS and RFS rates were similar between the group A and B patients (75.6 vs. 76.9%; P=0.5537; and 71.9 vs. 62.2%; P= 0.192, respectively). The short-term outcomes and long-term survival following colorectomy for colorectal adenocarcinoma among patients in the 70-79 years of age group, and those who were ≥80 in the current study were almost equal. Thus, it is not necessary to avoid colorectomy for colorectal adenocarcinoma in elderly patients simply because of their age.

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Are there any differences between age groups regarding colorectal surgery in elderly patients?

Cited by 26 publications

References 11 publications

Outcome of Colorectal Surgery in Elderly Populations

Outcome of Colorectal Surgery in Elderly Populations

Clinical characteristics and prognosis of elderly patients with colorectal cancer: comparison between surgical resection and supportive care

Evaluation of safety, feasibility and the long-term outcomes of colorectomy for colorectal adenocarcinoma in patients older than 80 years of age

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