Are there ethnic differences in the circadian variation in onset of acute myocardial infarction?

López, Francisca; Lee, Kaeng W.; Marı́n, Francisco; Roldán, Vanessa; Sogorb, Francisco; Caturla, J; Lip, Gregory Y.H.

doi:10.1016/j.ijcard.2004.12.002

Cited by 29 publications

(29 citation statements)

References 19 publications

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“…Lopez et al reported a difference in the onset of AMI among British Caucasians, Indo-Asians and Mediterranean Caucasians. 15 However, there has not been a large-scale study in …”

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confidence: 99%

Periodic Variation and Its Effect on Management and Prognosis of Korean Patients With Acute Myocardial Infarction

Park

Koo

Lee

et al. 2010

Circ J

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Background:The characteristics of the periodic variation in acute myocardial infarction (AMI) and the subsequent effect on management and prognosis have not been fully investigated in a large number of Asian populations. Methods and Results:From a prospective, observational multicenter online registry, 4,573 patients diagnosed as AMI in Korea from January to December 2006 were included. The highest incidence of AMI was between 8 a.m. and noon. The number of cases was highest in the winter and lowest in the autumn (13.6 vs 11.4 patients per day, P<0.001). Patients with symptom onset during working hours had a shorter time to first medical contact (203±288 min) compared with out-of-hours onset (230±288 min, P=0.003). In patients who underwent primary angioplasty, out-of hours symptom onset was associated with a greater time delay in both the patient's and the medical facility's response (door-to-balloon time out-of hours vs working hours: 101±54 min vs 84±44 min, P<0.001). In patients with ST-segment elevation myocardial infarction, symptoms to first medical contact showed a significant relationship to in-hospital mortality (for every 10 min of symptoms to first medical contact, odds ratio 1.006, 95% confidence interval 1.001-1.012, P=0.018) Conclusions: Circadian and periodic variation in AMI exists in Korean patients, which resulted in different patient behavior, hospital management and outcomes. (Circ J 2010; 74: 970 - 976)

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“…Lopez et al reported a difference in the onset of AMI among British Caucasians, Indo-Asians and Mediterranean Caucasians. 15 However, there has not been a large-scale study in …”

mentioning

confidence: 99%

Periodic Variation and Its Effect on Management and Prognosis of Korean Patients With Acute Myocardial Infarction

Park

Koo

Lee

et al. 2010

Circ J

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“…However, Erdogan et al recently reported that prior use of statin did not impact circadian periodicity of STEMI. Although a morning peak of the onset of STEMI is very common, especially in western countries, several studies have reported a secondary peak at noon [16,17]. Lunch is usually the main meal of the day in some countries including Turkey.…”

Section: Discussionmentioning

confidence: 99%

“…These differences may have affected the circadian rhythm. Some studies have revealed that different circadian periodicity of STEMI results from not only ethnic differences but also patients' characteristics and lifestyle [17]. The presence of diabetes and other cardiovascular risk factors, smoking, eating habits, light and dark cycle, and sleep patterns may affect the circadian periodicity of cardiovascular events [16].…”

Section: Discussionmentioning

confidence: 99%

The effect of Ramadan fasting on circadian variation of Turkish patients with acute myocardial infarction

Türker¹,

Aydın²,

Aslantaş³

et al. 2012

pwki

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A b s t r a c tIntroduction: The mechanisms of circadian variation in cardiovascular events are not clear. Aim: Evaluation of the effect of Ramadan fasting on circadian variation of acute ST-elevation myocardial infarction (STEMI) in Turkish patients.Material and methods: This comparative cross-sectional study included 151 consecutive patients with acute STEMI. The time of onset of STEMI was determined by the attending physician on the basis of patients' self-reports. The patients were divided into two group based on the history of fasting. The standard hourly profile of the onset of STEMI was obtained over a 24-h period. Patients were then categorized into four 6-hour increments according to the time that the symptoms began (00:00-05:59; 06:00-11:59; 12:00-17:59 and 18:00-23:59 h).Results: In all study participants, the highest incidence of STEMI was between 12.00 and 18.00; the odds ratio was 2.77 (95% CI: 2.63-2.92, p < 0.001). In the non-fasting group, the highest incidence of STEMI occurred between 06:00 and 12:00 A.M. The highest incidence of AMI occurred between 12.00 A.M. and 18.00 in patients with fasting; the odds ratio was 2.70 (95% CI: 2.51-2.91, p < 0.001). There were significant differences between fasting and non-fasting groups regarding circadian variation of STEMI (p < 0.001).Conclusions: There are significant changes in the circadian variation of patients with STEMI in relation to Ramadan fasting.

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“…Accordingly, Sarı et al (14) recently reported that there was an afternoon predominance in circadian variation of AMI in a Turkish cohort. On the other hand, some studies have revealed that different circadian periodicity of AMI results from not only ethnic differences but also patients' characteristics and lifestyle (15). The presence of diabetes and other cardiovascular risk factors, smoking, eating habits, light and dark cycle, sleep patterns may affect the circadian periodicity of cardiovascular event.…”

Section: Discussionmentioning

confidence: 99%

Influence of statin therapy on circadian variation of acute myocardial infarction

Erdoğan¹,

Ozaydin²,

Türker³

et al. 2010

Anadolu Kardiyol Derg

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Objective: Strong evidence has suggested that there is a circadian periodicity of acute coronary event. Beta-blockers, aspirin and angiotensinconverting enzyme inhibitors decrease the rate of acute myocardial infarction (AMI) and blunt the peak incidence in the morning. However, such effect has not been evaluated for statins. Accordingly, the present study aimed to evaluate the influence of statin therapy on circadian variation of AMI. Methods: This retrospective study consisted of 451 consecutive patients with acute ST segment elevation AMI. The patients were divided into two group based on prior statin usage. In statistical analysis t test, Chi-square test and Mann Whitney U test were used for comparison of groups. We used harmonic regression models to evaluate the circadian variation of onset of MI symptoms in patients receiving statin and patients not receiving statin. Results: In all study participants, the highest incidence of AMI was between 6.00 and 12.00; the odds ratio was 1.34 (95% CI 1.20 to 1.46, p<0.001). In the non-statin group, the highest incidence of AMI occurred between 0:00 A.M. and 06.00. There was still a peak incidence between 6.00 A.M. and noon in the statin therapy receiving group; the odds ratio was 1.61 (95% CI 1.34 to 1.80, p<0.001). Accordingly, there was no statistical difference between the statin and non-statin groups regarding circadian variation of AMI. Prior usage of statin did not blunt the peak incidence of AMI in the morning.

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Are there ethnic differences in the circadian variation in onset of acute myocardial infarction?

Cited by 29 publications

References 19 publications

Periodic Variation and Its Effect on Management and Prognosis of Korean Patients With Acute Myocardial Infarction

Periodic Variation and Its Effect on Management and Prognosis of Korean Patients With Acute Myocardial Infarction

The effect of Ramadan fasting on circadian variation of Turkish patients with acute myocardial infarction

Influence of statin therapy on circadian variation of acute myocardial infarction

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