Are there fitness costs of adaptive pyrethroid resistance in the amphipod, Hyalella azteca?

Heim, Jennifer R.; Weston, Donald P.; Major, Kaley M.; Poynton, Helen C.; Hartz, Kara E. Huff; Lydy, Michael J.

doi:10.1016/j.envpol.2017.12.043

Cited by 37 publications

(23 citation statements)

References 32 publications

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“…For populations with sufficient size and standing genetic variation, evolutionary rescue may occur (Bell & Gonzalez, ), but could be associated with “genetic erosion” or a reduction in genetic diversity through a bottleneck and subsequent founder effect (Van Straalen & Timmermans, ). In support of this theory, there is evidence that pyrethroid‐resistant H. azteca exhibit increased fitness costs, including a decrease in thermal tolerance and a tendency for greater sensitivity to other chemicals (Heim et al, ). In addition, given their ability to survive at concentrations of pyrethroids two orders of magnitude higher than wild‐type animals, increased bioaccumulation of pyrethroids in resistant H. azteca has been shown, leading to an increased risk of pyrethroid trophic transfer to their fish predators (Muggelberg et al., ).…”

Section: Discussionmentioning

confidence: 96%

Unintentional exposure to terrestrial pesticides drives widespread and predictable evolution of resistance in freshwater crustaceans

Major

Weston

Lydy

et al. 2018

Evolutionary Applications

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Pesticide runoff from terrestrial environments into waterways is often lethal to freshwater organisms, but exposure may also drive evolution of pesticide resistance. We analyzed the degree of resistance and molecular genetic changes underlying resistance in Hyalella azteca, a species complex of freshwater crustaceans inadvertently exposed to pesticide pollution via runoff. We surveyed 16 waterways encompassing most major watersheds throughout California and found that land use patterns are predictive of both pyrethroid presence in aquatic sediments and pyrethroid resistance in H. azteca. Nonsynonymous amino acid substitutions in the voltage‐gated sodium channel including the M918L, L925I, or L925V confer resistance in H. azteca. The most frequently identified mutation, L925I, appears to be preferred within the species complex. The L925V substitution has been associated with pyrethroid resistance in another insect, but is novel in H. azteca. We documented a variety of pyrethroid resistance mutations across several species groups within this complex, indicating that pyrethroid resistance has independently arisen in H. azteca at least six separate times. Further, the high frequency of resistance alleles indicates that pesticide‐mediated selection on H. azteca populations in waterways equals or exceeds that of targeted terrestrial pests. Widespread resistance throughout California suggests current practices to mitigate off‐site movement of pyrethroids are inadequate to protect aquatic life from negative ecological impacts and implies the likelihood of similar findings globally.

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Section: Discussionmentioning

confidence: 96%

Unintentional exposure to terrestrial pesticides drives widespread and predictable evolution of resistance in freshwater crustaceans

Major

Weston

Lydy

et al. 2018

Evolutionary Applications

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“…Only three other studies documented that resistance against one pesticide caused an increased vulnerability against another pesticide. [19][20][21] For example, the indoxacarb-resistant cotton bollworm Helicoverpa armigera was more susceptible to abamectin and methoxyfenozide. 19 Such costs have been explained by two mechanisms depending on how resistance is realized.…”

Section: Effects Of Single Exposure To (Bio)pesticides and Predator Cuesmentioning

confidence: 99%

“…On the other hand, resistant organisms might also be more sensitive to another pesticide due to the cost of resistance . Yet, this has been much less documented . One rare example is the finding that a pyrethroid‐resistant amphipod Hyalella azteca population showed a frequent tendency to be more sensitive to DDT, sodium chloride and copper (II) sulfate .…”

Section: Introductionmentioning

confidence: 99%

“…18 Yet, this has been much less documented. [19][20][21] One rare example is the finding that a pyrethroid-resistant amphipod Hyalella azteca population showed a frequent tendency to be more sensitive to DDT, sodium chloride and copper (II) sulfate. 20 Intriguingly, some studies even documented that synergistic interactions between pesticides (e.g.…”

Section: Introductionmentioning

confidence: 99%

“…[19][20][21] One rare example is the finding that a pyrethroid-resistant amphipod Hyalella azteca population showed a frequent tendency to be more sensitive to DDT, sodium chloride and copper (II) sulfate. 20 Intriguingly, some studies even documented that synergistic interactions between pesticides (e.g. 22,23 ), and between synthetic pesticides and biopesticides, 24,25 may partially overcome the resistance against synthetic pesticides in mosquitoes.…”

Section: Introductionmentioning

confidence: 99%

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Effects of predator cues and pesticide resistance on the toxicity of a (bio)pesticide mixture

Delnat

Janssens

Stoks

2019

Pest Management Science

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BACKGROUND Populations of target species are typically exposed to pesticide mixtures and natural stressors such as predator cues, and are increasingly developing resistance to single pesticides. Nevertheless, we have poor knowledge whether natural stressors and the presence of pesticide resistance shape mixture toxicity. We tested the single and combined effects of the pesticide chlorpyrifos and the biopesticide Bacillus thuringiensis israelensis (Bti) on the survival of the Southern house mosquito (Culex quinquefasciatus, Say) and whether these effects were magnified by synthetic predator cues of Notonecta water bugs and differed between a chlorpyrifos‐resistant (Ace‐1R) and non‐resistant (S‐Lab) strain. RESULTS Single exposure to Bti caused mortality in both strains (S‐Lab ∼27%, Ace‐1R ∼41%) and single exposure to chlorpyrifos caused only mortality in the S‐Lab strain (∼33%), while predator cues did not induce mortality. The chlorpyrifos‐resistant strain was 1.5‐fold more sensitive to Bti, indicating a cost of resistance. The interaction types between chlorpyrifos and Bti (additive), between chlorpyrifos and predator cues (additive), and between Bti and predator cues (synergistic) were consistent in both strains. Despite predator cues making Bti approximately 8% more lethal, they did not change the additive interaction between Bti and chlorpyrifos in their mixture in either strain. CONCLUSION These results indicate that the resistance against chlorpyrifos was not partly lifted when chlorpyrifos exposure was combined with Bti and predator cues. Identifying the interaction type within pesticide mixtures and how this depends on natural stressors is important to select control strategies that give a disadvantage to resistant individuals compared to non‐resistant individuals. © 2019 Society of Chemical Industry

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Epigenetics in Aquatic Toxicology

Hutton

Brander

2023

Epigenetics in Aquaculture

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Are there fitness costs of adaptive pyrethroid resistance in the amphipod, Hyalella azteca?

Cited by 37 publications

References 32 publications

Unintentional exposure to terrestrial pesticides drives widespread and predictable evolution of resistance in freshwater crustaceans

Unintentional exposure to terrestrial pesticides drives widespread and predictable evolution of resistance in freshwater crustaceans

Effects of predator cues and pesticide resistance on the toxicity of a (bio)pesticide mixture

Epigenetics in Aquatic Toxicology

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