Are There Mandibular Morphological Differences in the Various Facial Asymmetry Etiologies? A Tomographic Three-Dimensional Reconstruction Study

López, Diego Fernando; Botero, Juliana Ruiz; Muñoz, Juan Manuel; Cárdenas-Perilla, Rodrigo; Moreno, Mauricio

doi:10.1016/j.joms.2019.05.020

Cited by 13 publications

(29 citation statements)

References 54 publications

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“…Bone SPECT is very useful and has been validated for early diagnosis of UCH [ 1 , 6 , 7 , 22 ], because this is a condition that could be active during growth and development, but may be self-limited and finally expressed only by sequelae of the pathology [ 2 , 23 ]. Although the diagnosis is strictly clinical, based on intraoral and extraoral findings and tomographic or radiographic images, the evaluation of bone metabolism by SPECT is very useful to differentiate the active/inactive stages [ 17 ].…”

Section: Discussionmentioning

confidence: 99%

“…Taking into account these observations, the authors of the present study postulate that the specificity of the SPECT test is improved by the clinical and tomographic pre-diagnostic findings [ 17 ], and by the technique applied. The ROI selection; the number of trans-axial sections; and the quantification of radioactive uptake, either by total counts or mean counts, are critical aspects having an influence on the results of the test [ 18 ].…”

Section: Discussionmentioning

confidence: 99%

“…Therefore, a significant outcome of the study is the demonstration that a mandibular deviation >6 mm is able to classify the UCH condition as active or inactive, because the AUC in the ROC curve was 0.695. López et al [ 30 ] recently evaluated the ability of mandibular deviation to differentiate the hemi-mandibular elongation (the most common form of condylar hyperplasia [ 17 ]) from the asymmetric mandibular prognathism, determining that MDs >5.1 mm are more frequent in hemi-mandibular elongation cases.…”

Section: Discussionmentioning

confidence: 99%

“…The patients had been sent to Nuclear Medicine by the clinical specialists owing to facial asymmetry and suspected UCH. Following the classification of Lopez et al 2019 [ 17 ], the patients were classified by types of facial asymmetry, obtaining 71 cases with UCH diagnosis. Taking into account the information from clinical records, patients with antecedents of TMJ trauma or fracture, previous orthognatic surgery, dentofacial syndromes, and arthritis were excluded.…”

Section: Materials and Methods/patientsmentioning

confidence: 99%

“…The tomographic measurements were taken by a trained and calibrated operator. Each data set was simultaneously revised and classified according to the craniofacial characteristics of the asymmetry [ 17 ], together by the operator and a specialist with experience in diagnosis and treatment of patients with facial asymmetry.…”

Section: Materials and Methods/patientsmentioning

confidence: 99%

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SPECT/CT Correlation in the Diagnosis of Unilateral Condilar Hyperplasia

et al. 2021

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Objective: To evaluate the correlation between metabolic bone activity measured by single photon emission computed tomography (SPECT) and the anatomic condylar characteristics acquired by computed tomography (CT), in patients with unilateral condylar hyperplasia (UCH). Method and Materials/Patients: Observational, descriptive study in a group of 71 patients with clinical diagnosis of UCH and indication of SPECT/CT. Bone SPECT images obtained in a gamma-camera GE Infina and processed in a station Xeleris 3 with the program Volumetrix MI Evolution for bone. CT images acquired in a PET/CT Biograph mcT20 equipment (Siemens) processed in a station Osirix V 7.5.1 (Pixmeo, Bomex, Switzerland). Results: The sample included 24 men (33.8%) and 47 women (66.2%). Active state UCH was detected in 40 (56.3%) cases (over 55% uptake in the affected condyle) and 38 (53.5%) presented mandibular deviation to the right side. No significant differences related to sex, age, or mandibular deviation side were found. Mandibular deviation was the only morphologic feature related to active/inactive UCH (p = 0.003). The likelihood of active CH was significantly higher in patients with mandibular deviation higher than 6 mm compared with <6 mm (odds ratio (OR): 3.51, confidence interval (CI) 95%: 1.27–9.72). Conclusion: There is a significant correlation between the magnitude of mandibular deviation quantified on CT and metabolic findings obtained by SPECT in patients with UCH. The risk of active UCH is 3.5 times higher in patients with a mandibular deviation =>6 mm.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Materials and Methods/patientsmentioning

confidence: 99%

Section: Materials and Methods/patientsmentioning

confidence: 99%

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SPECT/CT Correlation in the Diagnosis of Unilateral Condilar Hyperplasia

et al. 2021

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Volumetric differences in temporomandibular joint components in patients with facial asymmetry: A 3D tomographic segmentation study

López,

Giraldo,

Borrás

et al. 2024

Seminars in Orthodontics

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Reference values of mandibular condyles metabolic activity: A study using ^99mTc‐MDP single‐photon emission computed tomography

López

Castro

Muñoz

et al. 2020

Orthod Craniofacial Res

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Objective: To assess the condylar bone metabolic activity in patients with temporomandibular joint health by measuring 99m Tc-MDP uptake using a single-photon emission computed tomography (SPECT) to establish reference values of the uptake difference between condyles and the ratio with respect to the clivus.Setting and sample population: Eighty consecutive patients of both sexes who were admitted to a Nuclear Medicine Centre between 2017 and 2019 were included in the study. Method:This was an observational cross-sectional study in patients with SPECT indications to evaluate pathologies other than those of the temporomandibular joint.The values of the total and normalized counts in a fixed region of interest of five trans-axial slides were obtained to assess the percentage difference between the sides and the uptake ratio. The reference values are expressed as median and 5th and 95th percentiles. Results:The sample included 53 women (66.25%) and 27 men (33.75%) aged 15-55 years. The percentage of uptake difference between condyles was 5.04% (0.46-14.78) for men and 5.17% (0.27-13.21) for women (difference not significant, P = .9). The uptake difference was below 10% in 85% of the subjects (n = 68). The ratio values for total counts in women (0.87, 0.46-1.33) were significantly different (P = .0030) from those in men (1.08, 0.61-2.09). No significant correlation with age was found.Conclusions: These new reference ranges are applicable to the diagnosis of unilateral and bilateral condylar hyperplasia.

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Are There Mandibular Morphological Differences in the Various Facial Asymmetry Etiologies? A Tomographic Three-Dimensional Reconstruction Study

Cited by 13 publications

References 54 publications

SPECT/CT Correlation in the Diagnosis of Unilateral Condilar Hyperplasia

SPECT/CT Correlation in the Diagnosis of Unilateral Condilar Hyperplasia

Volumetric differences in temporomandibular joint components in patients with facial asymmetry: A 3D tomographic segmentation study

Reference values of mandibular condyles metabolic activity: A study using ^99mTc‐MDP single‐photon emission computed tomography

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Are There Mandibular Morphological Differences in the Various Facial Asymmetry Etiologies? A Tomographic Three-Dimensional Reconstruction Study

Cited by 13 publications

References 54 publications

SPECT/CT Correlation in the Diagnosis of Unilateral Condilar Hyperplasia

SPECT/CT Correlation in the Diagnosis of Unilateral Condilar Hyperplasia

Volumetric differences in temporomandibular joint components in patients with facial asymmetry: A 3D tomographic segmentation study

Reference values of mandibular condyles metabolic activity: A study using 99mTc‐MDP single‐photon emission computed tomography

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Reference values of mandibular condyles metabolic activity: A study using ^99mTc‐MDP single‐photon emission computed tomography