Are we too reluctant about irrational nutraceutical combinations?

Krishnan, V. Gokula; Murugaiah, Prakash; Bachmann, Aruna Maria

doi:10.18203/2319-2003.ijbcp20164128

Cited by 2 publications

(2 citation statements)

References 8 publications

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“…Nutraceuticals, in general considered safe and their ill effects are unrecognised in our scenario. In diarrhoeal illness with or without symptoms like fever zinc currently not prescribed as per their recommendations which must be emphasized from the level of primary health care [9][10][11].…”

Section: Discussionmentioning

confidence: 99%

Rationality Assessment of Zinc Formulations Available in India

Chary

Bhaskaran

2017

Int J Pharm Pharm Sci

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Objective: To critically analyze the essentiality and irrational zinc preparations available in Indian market. Methods:This was conducted as cross-sectional analysis by department of pharmacology of our tertiary care hospital between June and December 2016. Data regarding various formulations of zinc were retrieved from current index of medical sciences and drug India database. Rationality assessment was done using prescribed guidelines and approved formulations of zinc by Central drug standard control organisation. Essentiality was checked using National list of essential medicine India, 2013 and latest version of WHO list essential medicine bulletin. Dosage regulation was assessed using Indian pharmacopeia guidelines, National institute of nutrition, India recommendation and upper daily intake toxicity intake, United States of America (USA) Results: Our study results showed wide variation in the number of zinc preparation. Total number of formulation available in the market is 335. Among zinc preparation, the preparation that contains 20 mg of zinc as recommended by various guidelines is 10 in number. About 325 preparations of zinc are added with one or more nutraceuticals. None of these fixed dose combination of zinc containing preparation is recommended as essential fixed regimen. Conclusion:Zinc has lot of relevance in treating recurrent diarrhoeal illness, especially in paediatric cases; however legal, regulatory and educational measures should be followed to curtail all the irrational zinc prescription development, promotion, marketing and prescription.

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Section: Discussionmentioning

confidence: 99%

Rationality Assessment of Zinc Formulations Available in India

Chary

Bhaskaran

2017

Int J Pharm Pharm Sci

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“…Researchers from India also reported that multivitamins are irrationally prescribed and taken as self-medication by the public. As many of the ill effects are often unnoticed and under-reported, they advised India's government to regulate the manufacture and sell these nutraceuticals to promote drugs' rational use (Krishnan et al, 2016). Therefore, pharmacology education should incorporate problem-oriented rational treatment programmes, provide rigorous supervision in prescribing during clinical training, offer higher quality in-service training, and continuous medical education to improve physicians' prescribing attitudes and skills and reduce irrational medicine use (Calikoglu et al, 2019).…”

Section: Irrational Use Of Drugs In Different Countriesmentioning

confidence: 99%

Irrational Use of Drugs

Rahman

Matanjun

D'Souza

et al. 2021

BJMS

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Irrational use of drugs could be detrimental issues in the practices of healthcare communities. This problem arises either because of the wrong prescription or inappropriate self-medication. Faulty prescribing practices and incorrect self-medication will lead to an ineffective treatment regime. Still, they can also be unsafe as these may exacerbate or prolong the illness and distress the patients. In turn, these will incur unnecessary treatment costs. The most typical issues in the irrational use of drugs are the patient’s lack of information about the medicine and inadequate proper consultation from physicians. Lack of regulation in the appropriate use and supply of drugs by the relevant enforcement agencies could also be the problem in the irrational use of drugs. Ulceration and inflammation due to the irrational use of NSAIDs, antibiotics, and unhealthy lifestyle may contribute to the novel therapeutic strategy challenges. The ability to purchase the drugs without a doctor’s prescription of nonsteroidal anti-inflammatory drugs (NSAIDs) was also the landmark event that became the most widely used medications for the anti-inflammatory, analgesic, and antipyretic effects. Inadequate knowledge from both drug providers and patients may contribute to the most recognized influential factors in the irrational use of drugs in various countries. The recommendation should introduce an appropriate educational intervention that can be designed to promote rational prescribing. Proper regulation on prescription practices by policymakers and physicians could be the way to ensure the standard of rational usage of drugs have compliant with the healthcare communities.

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Are we too reluctant about irrational nutraceutical combinations?

Cited by 2 publications

References 8 publications

Rationality Assessment of Zinc Formulations Available in India

Rationality Assessment of Zinc Formulations Available in India

Irrational Use of Drugs

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